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EPA Research

EPA Research. Ramona Trovato Jeff Morris March 29, 2011. What is Sustainability? . Development that meets the needs of the present without compromising the ability of future generations to meet their own needs. —Brundtland Commission, 1987. regulate. evaluate , purchase. educate.

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EPA Research

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  1. EPA Research Ramona Trovato Jeff Morris March 29, 2011

  2. What is Sustainability? Development that meets the needs of the present without compromising the ability of future generations to meet their own needs. —Brundtland Commission, 1987

  3. regulate evaluate, purchase educate Systems Approach Society Industry evaluate, purchase collaborate, catalyze collaborate,catalyze Innovate innovate regulate research regulate research research protect, restore facilitate protect, restore facilitate Environment

  4. ORD National Research Programs Human Health Risk Assessment Homeland Security

  5. Portfolio Webinar Date: 03/21/11 Webinar: Built Environment Date: 04/06/11 01:00 PM – 2:00 PM 3/1 12:00 PM Stakeholder Webinar R10 Listening Session in Eugene-Springfield, OR Date: 03/30/11 ACE CSS SHCRP SSWR Partner Meeting RTP Date: 03/28/11 Webinar: Nutrient Loading Date: 04/14/11 01:00 PM – 2:00 PM 3/15 12:00 PM Stakeholder Webinar R10 Listening Session in Spokane, WA Date: 04/01/11 Webinar: Agriculture Date: 04/20/11 01:00 PM – 2:00 PM R2 Listening Session in Wyandanch, NY Date: 04/06/11 01:00 PM – 3:00 PM Webinar: Water Ecosystems Protection Date: 04/26/11 01:00 PM – 2:00 PM Listening Session R1 in Boston, MA Date: 04/07/11 01:00 PM – 2:00 PM Webinar: Energy/ Materials Extraction Date: 05/05/1 11:00 PM – 2:00 PM Listening Session R4 in Asheville, NC Date: 04/12/11 08:30 AM – 4:00 PM Webinar: Chemicals Date: 05/11/11 01:00 PM – 2:00 PM SHCRP Community Engagement Meeting in Durham, NC Date: 04/20/11 SHCRP External Key Leaders Partners Meeting in RTP, NC Date: 04/13/11 Opportunities for Input and Direction SHCRP EPA Stakeholder Integrated Meeting Dates: 04/26/11 – 04/27/11 SHCRP: ORD Multi Partner Meeting in RTP, NC Dates: 04/28/11 – 04/29/11

  6. Context: The Chemicals Situation Many Chemicals Little Data (%) Judson, et al EHP (2009)

  7. Why Is It Time to Change How EPA Conducts Chemicals Research? Because new technology and greater knowledge give us the opportunity to . . .introduce new substances, such as carbon nanotubes . . . Source: NASA . . . in a more environmentally sustainable way than we were able to do with substances such as asbestos in the 20th century . . . Source: ATSDR . . . and provide more efficient tools for assessments. HTS Robotic Platform

  8. Example of a Potential Game Changer: ToxCast enabling more chemical assessments using less resources ? $6M 2 years $2B 30 years Traditional Toxicology Computational Toxicology

  9. Generating Data to Support an Integrated Evaluation Strategy: An Nanomaterials Example Physicochemical Characterization Selected specific nanoparticle types based on EPA and international (OECD) priorities Well-characterized manufactured nanomaterials, and transformation products Data on fate, transport, and transformation in air, water, soil, food Alternative Test Methods (Non-Cellular and Cellular Based Assays) In Vivo Toxicology -Screen/Rank -Design In Vivo Testing -Identify and Validate Alternative In Vitro Tests Predictive of In Vivo Toxicity

  10. Identifying what properties of specific materials may cause them to be hazardous and/or mobile, persistent, or bioavailable (e.g., nano-cerium fuel additives) Developing lifecycle assessment methodologies to understand inputs and releases from the development, use, and disposal/recycling of nanomaterials (e.g., lifecycle assessment of nano-enabled lithium-ion batteries) Testing green chemistry approaches that can lead to creating nanoparticles with low environmental impact Green Chemistry Opportunities EPA is seeking to advance safe, sustainable nanomaterials by:

  11. Priority Science Needs (beyond R&D, beyond EPA) to Better Inform Policy Decisions Green chemistry and safer-by-design research that advances sustainable nanotechnology New decision-analysis approaches to more quickly and effectively use scientific information to inform decisions that weigh the benefits and impacts of technologies across product life cycles Enhanced scientific collaborations within and across all sectors: government (including state and local), industry, and academia See www.css.ideascale.com for more on ORD chemical safety research

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