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WHO Policy on TB Infection Control in Healthcare Facilities, Congregate Settings and Households

New. WHO Policy on TB Infection Control in Healthcare Facilities, Congregate Settings and Households. Michele L. Pearson, MD International Research and Programs Branch Division of TB Elimination. Outline. Global global TB trends and healthcare-associated TB transmission

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WHO Policy on TB Infection Control in Healthcare Facilities, Congregate Settings and Households

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  1. New WHO Policy on TB Infection Control in Healthcare Facilities, Congregate Settings and Households Michele L. Pearson, MD International Research and Programs Branch Division of TB Elimination

  2. Outline • Global global TB trends and healthcare-associated TB transmission • Process/methods used to develop WHO TB IC policy • Summary of new TB IC recommendations and policy changes since previous document • Recommended practices for biosafety

  3. Rationale of TB IC • Co-existing HIV pandemic • Emergence of MDR/XDR-TB strains • Documented TB transmission and outbreaks in healthcare settings • Implementation of recommended TB infection control interventions terminated or reduced facility TB transmission

  4. Wells, C et al. JID 2007;196:S86–S107

  5. Importance of TB Infection Control • Subcomponent of WHO’s updated Stop TB Strategy, contributing to health system strengthening • Element of WHO’s 12 collaborative activities for TB and HIV control • One of WHO’s “Three I’s for HIV/TB” • Essential component of sound HIV control programs in countries with high HIV prevalence

  6. Status of Global TB IC Efforts, 2008 • 66% (131/199) of WHO Member States reported having TB IC plan • None reported data on implementation

  7. WHO Policy on TB IC • Objective: Provide member States with guidance on how to reduce TB transmission in healthcare facilities and how to prioritize TB IC measures • Target audience: • Policy makers (national and subnational) • Managers of TB and HIV/AIDS programs • IC and quality assurance programs/personnel • Occupational health • Documented TB transmission and outbreaks in healthcare settings

  8. What’s New • Guidance on how to prioritize TB IC measures at National level, including national managerial activities • Update on facility-level measures • Considers facility-level managerial activities as a separate element, rather than a component of administrative controls • Emphasis on appropriate administrative and environmental controls and personal protective equipment

  9. What’s New? • Special focus on building design and use of space • Increased emphasis on certain activities: • Integration of TB IC with other healthcare system efforts • Greater involvement of civil society in design, development, implementation, and monitoring and evaluation of TB IC • Greater emphasis on selective administrative controls (e.g., reduction in time spent in healthcare facilities) • Provision of HIV prevention, treatment and care services for health workers

  10. Policy Formulation Process

  11. Policy Formulation Process • Systematic review panel reviewed science on efficacy and effectiveness of TB IC measures • Collaborative effort of WHO Department for Epidemic and Pandemic Alert and Response, HIV/AIDS Department and the Patient Safety Programme • Draft reviewed by various stakeholders, including systematic review panel, WHO regional office staff, TB IC sub-group of WHO TB/HIV working group, implementation working group of Stop TB Partnership • Recommendations expected to remain valid until 2013

  12. Recommendation Rankings • Strong--desirable effects outweigh undesirable effects • Conditional—desirable effects probably outweigh undesirable effects) • Recommendations also informed by expert opinion, climatic, cultural, cost and programmatic factors

  13. Factors that Influence Recommendation Rankings • Quality of evidence • Benefits • Values and preferences • Costs • Feasibility

  14. Other Outcomes of Systematic Review • Identified gaps in science on efficacy and effectiveness of TB IC measures • Need for scale-up in TB IC research • Highlighted importance of simple indicators to monitor success in implementing TB IC programs/activities

  15. WHO TB IC Policy for Healthcare Settings • Policy complements: • General infection control efforts • Airborne infection control efforts • Describes how to prioritize TB IC measures based on burdens of TB, HIV and MDR-TB • Does not provide recommendations on laboratory biosafety • Stresses importance of sustained political, institutional, and financial commitment and multidisciplinary involvement

  16. National and Subnational Activities

  17. National and Subnational TB IC Activities • Describes six activities that provide the managerial framework for implementation of TB IC in healthcare settings • Targeted to policy makers at national and subnational levels

  18. National and Subnational TB IC Activities • Identify and strengthen a coordinating body for TB IC and develop comprehensive budgeted plan that includes necessary human resources for program implementation • Ensure appropriate facility design, construction, renovation and use • Conduct surveillance of TB among HCWs and conduct assessments at all levels of the healthcare delivery system • Address TB IC advocacy, communication, social mobilization (ACSM), including civil society engagement • Monitor and evaluate TB IC measures • Enable and conduct operational research

  19. Reducing TB transmission in health-care facilities

  20. Facility-level TB IC Measures • Managerial Activities (Facility-level) • Identify and strengthen local coordinating bodies for TB IC and develop facility implementation plan (including human resources, and policies and procedures to ensure proper implementation of controls) • Conduct on-site surveillance of HCWs for TB disease and assess facility • Rethink use of available spaces and consider renovation of existing facilities or construction of new ones to optimize implementation of controls • Address advocacy, communication and social mobilization (ACSM) for HCWs, patients and visitors • Monitor and evaluate set of TB IC measures • Participate in research efforts

  21. Facility-level TB IC Measures • Administrative controls • Prompt detection of patients w/ TB sxs (triage), separation of infectious patients, cough etiquette and respiratory hygiene, minimize time in facility, decrease diagnostic delays (use of rapid diagnostics, decrease time for sputum testing and culture), prompt treatment • Package of prevention and care interventions for HCWs including HIV prevention, ART and IPT for HIV-positive HCWs • Environmental controls • Use ventilation systems • Use UV germicidal irradiation (UVGI) fixtures, at least when adequate ventilation can not be achieved • Personal protective equipment • Use particulate respirators

  22. Administrative Controls: Strength of recommendation and Evidence Quality Evidence Quality Recommendation

  23. Administrative Controls: Strength of recommendation and Evidence Quality Evidence Quality Recommendation

  24. Environmental Controls: Strength of recommendation and Evidence Quality Evidence Quality Recommendation

  25. Personal Protective Equipment: Strength of recommendation and Evidence Quality Evidence Quality Recommendation

  26. Prioritizing Measures and Setting Targets for TB IC

  27. Prioritization of TB IC Measures • Identify and strengthen a coordinating body for TB IC and develop comprehensive budgeted plan that includes necessary human resources for program implementation • Ensure appropriate facility design, construction, renovation and use • Conduct surveillance of TB among HCWs and conduct assessments at all levels of the healthcare delivery system • Address TB IC advocacy, communication, social mobilization (ACSM), including civil society engagement • Monitor and evaluate TB IC measures • Enable and conduct operational research

  28. Suggested targets: Global-level implementation of TB IC

  29. Summary • TB transmission in healthcare settings poses risk to patients and HCWs and undermines global TB control efforts • WHO TB IC policy • provided evidence-based, cost-effective, feasible recommendations for TB IC • identified gaps in science on efficacy and effectiveness of TB IC measures • highlighted need for scale-up in TB IC research • stressed importance of simple indicators to monitor success in implementing TB IC programs/activities • prioritized TB IC efforts

  30. Research Gaps • Administrative controls • Impact of cough etiquette/respiratory hygiene on TB transmission • Rapid diagnostics to reduce time to diagnosis • Screening criteria for triaging TB suspects in different settings based on TB, HIV and MDR/XDR-TB burdens • Effect of physical separation based on smear results, HIV status and drug-susceptibility pattern • Methods for screening HCWs • Duration of preventive therapy

  31. Research Gaps • Environmental controls • Effectiveness of ventilation systems in different settings and climates and by design • Efficacy and effectiveness of UVGI • Personal Protective Equipment • Impact of fit-testing on effectiveness • Re-use guidance

  32. WHO Policy on TB Infection Control in Healthcare Facilities, Congregate Settings and Households

  33. Muchas Gracias! mpearson@cdc.gov

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