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Treatment of cough

Treatment of cough . By :ISRAA OMAR. COUGH. It is a protective reflex that removes foreign material and secretion from the bronchi and bronchioles.

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Treatment of cough

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  1. Treatment of cough By :ISRAA OMAR

  2. COUGH • It is a protective reflex that removes foreign material and secretion from the bronchi and bronchioles. • It is very common adverse effect of the angiotensin-converting enzyme inhibitors, in which case ,the drug should be changed in to alternative drug . • It can be triggered by inflammation in the respiratory system ,for example asthma, pneuomnia,forign body, heart failure, URTI chronic reflux with aspiration, or by neoplasia

  3. Antitussive • Antitussive drugs act by ill defined effect in the brain stem , depressing an even more poorly defined “cough center”. • All opioid narcotic analgesic have antitussive narcotic analgesic in doses lower than those required for pain relief • They have minimum analgesic and addictive properties • Newer agent that only act peripherally on sensory nerves in bronchi are being assessed

  4. CODIENE • It is the gold standard treatment for cough suppression • It decreases the sensitivity of cough center in the CNS to peripheral stimuli, decrease the mucosal secretion which thicken the sputum, and inhibit ciliary activity • These therapeutic effect occur at doses lower than those required for analgesia but still incur common side effect like constipation, dysphoria, and fatigue, in addition to addiction potential

  5. DEXTROMETHORPHAN • Is a synthetic derivative of morphine that suppresses the response of the central cough center • It has no analgesic effect, has low addictive profile, but may cause dysphoria at higher doses • Has significantly better side effect profile than codeine and has been demonstrated to be equally effective for cough suppression

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