1 / 10

PHARMACEUTICAL MICROBIOLOGY-I

PHARMACEUTICAL MICROBIOLOGY-I. Presentation on Polio. Introduction.

charlesaustin
Download Presentation

PHARMACEUTICAL MICROBIOLOGY-I

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. PHARMACEUTICAL MICROBIOLOGY-I Presentation on Polio www.AssignmentPoint.com

  2. Introduction Polio or Poliomyelitis or infantile paralysis is an acute viral infectious disease spread from person to person, primarily via the fecal-oral route. Poliomyelitis was first recognized as a distinct condition by Jakob Heine in 1840.Its causative agent, poliovirus, was first identified in 1908 by Karl Landsteiner. www.AssignmentPoint.com

  3. Different types of polio Polio may be following types: • Paralytic polio: In around 1% of infections, poliovirus spreads along certain nerve fiber pathways, preferentially replicating in and destroying motor neurons within the spinal cord, brain stem, or motor cortex. This leads to the development of paralytic poliomyelitis. www.AssignmentPoint.com

  4. 2.Spinal polio: Spinal polio, the most common form of paralytic poliomyelitis, results from viral invasion of the motor neurons of the anterior horn cells. www.AssignmentPoint.com

  5. 3.Bulbar polio: Bulbar polio occurs when poliovirus invades and destroys nerves within the bulbar region of the brain stem. The bulbar region is a white matter pathway that connects the cerebral cortex to the brain stem. www.AssignmentPoint.com

  6. 4.Bulbospinal polio: Approximately 19% of all paralytic polio cases have both bulbar and spinal symptoms; this subtype is called respiratory or bulbospinal polio. Here, the virus affects the upper part of the cervical spinal cord (cervical vertebrae C3 through C5), and paralysis of the diaphragm occurs. www.AssignmentPoint.com

  7. Causes of Polio Poliomyelitis is caused by infection with a member of the genus enterovirus known as poliovirus (PV). This group of RNA viruses colonize the gastrointestinal tract specifically the oropharynx and the intestine. The incubation time (to the first signs and symptoms) ranges from three to 35 days, with a more common span of six to 20 days. PV infects and causes disease in humans alone. Its structure is very simple, composed of a single (+) sense RNA genome. Three types of poliovirus have been identified poliovirus type 1 (PV1), type 2 (PV2), and type 3 (PV3). All three are extremely virulent and produce the same disease symptoms.PV1 is the most commonly encountered form, and the one most closely associated with paralysis. Individuals who are exposed to the virus, either through infection or by immunization with polio vaccine, develop immunity. www.AssignmentPoint.com

  8. Sign and symptoms or effect • Abnormal sensation • Breathing difficulty • Difficulty swallowing • Urinary retention • Constipation • Drooling • Headache • Mood swings • Muscle pain and spasms • Paralysis. • Fever www.AssignmentPoint.com

  9. Treatment of Polio There is no cure for polio, so prevention is very important. Patients with non-paralytic polio need to be monitored for progression to paralytic polio. Patients with paralytic polio need to be monitored for signs and symptoms of respiratory failure, which may require lifesaving therapies such as respiratory support. In addition, a number of treatments are available to decrease some of the less severe symptoms. Patients who recover from polio may require physical therapy, leg braces, or even orthopedic surgery to improve physical function. www.AssignmentPoint.com

  10. Thank You!!! www.AssignmentPoint.com

More Related