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CARDIOVASCULAR DISEASE RISK ASSESSMENT. Cardiovascular disease (CVD) Definition. Cardio- = The Heart -Vascular= Blood Vessels Cardiovascular diseases = disease of The Heart + Blood vessels. Atherosclerosis. Blood vessels disease can occur everywhere!. STROKE. Coronary Heart Disease.
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Cardiovascular disease (CVD) Definition • Cardio- = The Heart • -Vascular= Blood Vessels • Cardiovascular diseases = disease of The Heart + Blood vessels
Cardiovascular Diseases Stroke Coronary Heart Disease Aortic Aneurysm Peripheral Artery Disease
Life time risk of Coronary Heart Disease • At 40 years old • 1 in 2 man • 1 in 3 woman Lifetime risk of developing coronary heart disease. Lloyd-Jones DM, Larson MG, Beiser A, Levy D Lancet. 1999;353(9147):89
Already in very high risk • Established cardiovascular disease • Diabetes • Chronic kidney disease
Cardiovascular disease & Diabetes Prediction of Lifetime Risk for Cardiovascular Disease by Risk factor Burden at 50 Years of Age Lloyd-Jones, DM, Leip. EP, Larson, MG et al, Circulation 2006; 113:791
Major risk factors • Increasing age • High cholesterol • High blood pressure • Smoking
Lifetime risk of Cardiovascular disease Risk factors • Cholesterol • BP • Smoking 70% 50% 5% 8% Prediction of Lifetime Risk for Cardiovascular Disease by Risk factor Burden at 50 Years of Age Lloyd-Jones, DM, Leip. EP, Larson, MG et al, Circulation 2006; 113:791
Median survival Risk factors (RF): • BP≥160/100 • Total Cholesterol ≥ 6.2 • Smoking Year
Cardiovascular disease – 10yr risk • The Framingham predictor • http://hp2010.nhlbihin.net/atpiii/calculator.asp?usertype=prof
Calculate the points according to your – Total cholesterol level
Major risk factors • Age (M≥45, F≥55) • Family history of heart attack or sudden death before 55years (M) or 65years (F) • Current cigarette smoking • High blood pressure 140/90mmHg or on treatment • HDL<1.03mmol/L • HDL>1.55mmol/L -> remove one risk factor
Thank you ; ) Wish you all a health heart
Cardiovascular disease & Blood pressure >160 140-159 130-139 <120 Prediction of Lifetime Risk for Cardiovascular Disease by Risk factor Burden at 50 Years of Age Lloyd-Jones, DM, Leip. EP, Larson, MG et al, Circulation 2006; 113:791
Cardiovascular disease & Total Cholesterol 6.19 5.16-6.18 4.64-5.15 <4.16 Prediction of Lifetime Risk for Cardiovascular Disease by Risk factor Burden at 50 Years of Age Lloyd-Jones, DM, Leip. EP, Larson, MG et al, Circulation 2006; 113:791
Major risk factors • Increasing age • High cholesterol • High “bad cholesterol” (LDL) • Low “good cholesterol” (HDL) • High blood pressure • Smoking • Family history of heart attack or sudden death • … • … • …
Borderline risk factors • Systolic pressure 120 to 139 mmHg • Diastolic pressure 80 to 89 mmHg • LDL-cholesterol 2.6 to 4.1 mmol/L • HDL-cholesterol 1.0 to 1.5 mmol/L • Impaired fasting glucose without overt diabetes • A past history of smoking
Total Chlos >=6.2 • SBP>=160 • DBP>=100 • Smoking • Diabetes • Non-optimal • Total chol 4.65-5.15 • SBP120-139 • DBP80-90