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pER ser 167

Fig 5. A. MCF7-AROM-1 basal (No E2) ER/ERE. MCF7-AROM1 And-mediated ER/ERE. Fold change in transcription relative to And control. Fold change in transcription relative to DCC control. *. +. + - - -. + + - -. + - + -. + + + -. + - - +. + + - +. +. And 10nM

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pER ser 167

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  1. Fig 5 A MCF7-AROM-1 basal (No E2) ER/ERE MCF7-AROM1 And-mediated ER/ERE Fold change in transcription relative to And control Fold change in transcription relative to DCC control * + + - - - + + - - + - + - + + + - + - - + + + - + + And 10nM RAD001 2nM Let 100nM 4-OHTam 10nM B BT474-AROM3 basal (No E2) ER/ERE BT474-AROM3 And-mediated ER/ERE * Fold change in transcription relative to And control Fold change in transcription relative to DCC control * * * + + - - - + + - - + - + - + + + - + - - + + + - + And 10nM RAD001 2nM Let 100nM 4-OHTam 10nM C LTED E2- mediated ER/ERE LTED basal (No E2) ER/ERE * * Fold change in transcription relative to DCC control Fold change in transcription relative to E2 control E2 0.01nM RAD001 2nM 4-OHTam 10nM + - - + + - + - + + + + D LTED + - - - + + - - + - + - + + + - + - + + + + + + DCC RAD001 2nM E2 0.01nM 4-OHTam 10nM pER ser118 0.19 0.15 0.82 0.87 0.70 0.87 pER ser167 0.86 0.02 0.11 0.02 1.39 0.01 ER pS6S240/S244 0.96 0.00 1.07 0.00 1.45 0.00 Actin

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