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Cephalosporins

Cephalosporins. Treatment of a wide range of bacteria including those sensitive to penicillin. 4 Groupings First Generation to Fourth Generation Increase sensitivity to gram negative decrease gram positive. . Cephalosporins. Actions Affect cell wall Typically bactericidal

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Cephalosporins

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  1. Cephalosporins • Treatment of a wide range of bacteria including those sensitive to penicillin. • 4 Groupings • First Generation to Fourth Generation • Increase sensitivity to gram negative decrease gram positive. Dr. Steven I. Dworkin

  2. Cephalosporins • Actions • Affect cell wall • Typically bactericidal • Adverse reactions • Gastrointestinal disturbances • Hypersensitivity • Headache, dizziness, nephrotoxicity, malaise, fever • Bacteria or fungal superinfection Dr. Steven I. Dworkin

  3. Dr. Steven I. Dworkin

  4. Dr. Steven I. Dworkin

  5. Broad-Spectrum Antibiotics • Tetracyclines, Macrolides, and Lincosamides • Tetracyclines • Anti-infectives natural and synthetic compounds • Treatment of cholera, Rocky Mountain spotted fever. • May cause permanent discoloration of teeth children under 9. • Macrolides • Effective against a wide variety of pathogenic organisms especially infections of respiratory and genital tracts. • Treatment of gram-negative and positive organisms. Dr. Steven I. Dworkin

  6. Broad-Spectrum Antibiotics • Tetracyclines, Macrolides, and Lincosamides • Lincosamides • Anti-infectives effective against gram-positive and gram-negative bacteria (streptococci and staphylococci). • High potential for toxicity limits use. Dr. Steven I. Dworkin

  7. Dr. Steven I. Dworkin

  8. Dr. Steven I. Dworkin

  9. Dr. Steven I. Dworkin

  10. Dr. Steven I. Dworkin

  11. Dr. Steven I. Dworkin

  12. Dr. Steven I. Dworkin

  13. Dr. Steven I. Dworkin

  14. Dr. Steven I. Dworkin

  15. Dr. Steven I. Dworkin

  16. Dr. Steven I. Dworkin

  17. Dr. Steven I. Dworkin

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  19. Dr. Steven I. Dworkin

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