HRB Centre for Primary Care Research Department of General Practice RCSI Medical School

1. HRB Centre for Primary Care ResearchDepartment of General PracticeRCSI Medical School Developing an International Register of CPRs for Primary Care: Identifying an Optimal Strategy to Search the Literature Claire Keogh Quality Assessment of CPR studies Emma Wallace

2. 1) Developing an international register of CPRs for primary care 2) Search strategies to identify CPRs relevant to primary care 3) Quality assessment of CPR studies

3. The International Register of CPRs for Primary Care

4. The International Register of CPRs for Primary Care Develop a register of CPRs for use in primary care Developed as part of the Cochrane Primary Health Care Field (http://www.cochraneprimarycare.org/en/index.html) Currently 239 relevant articles on the register

5. The International Register of CPRs for Primary Care • Problems associated with developing and maintaining the register • No internationally agreed term for CPRs • No internationally agreed term for primary care • No Medical Subject Heading (MeSH) term for CPRs • Over two million articles are published every year • Haynes and the Hedges Team have developed search tools to identify CPRs. These are not specific to primary care

6. Developing an electronic search strategy for MEDLINE

7. Electronic Search Filters: Method

8. Electronic Search Filters: Results

9. Electronic Search Filters: Results

10. Register

11. The International Register of CPRs for Primary Care

12. Quality assessment of CPR studies

13. Clinical prediction rules (CPRs) • CPRs are utilised in decisions regarding patient care • Quality of CPR studies of key importance • Clinicians need to be able to evaluate research • Need for clarity and accuracy in research reporting

14. Health research reporting

15. Health research reporting • International initiative ‘Equator’ set up in 2008 • Aim to provide resources and education enabling improvement of reporting and monitor progress and improvements • Develop network of reporting guidelines e.g. CONSORT, STARD, STROBE, PRISMA

16. Quality assessment of CPRs • Wasson et al, 1985, Laupacis et al, 1997, McGinn et al, 2000 • Specifically review methodological standards for CPR studies • Different quality markers for derivation and validation CPR studies

17. Quality assessment of CPRs • Currently piloting quality checklists for CPR studies on register • Combination of quality markers from available resources to develop CPR quality checklist e.g. QUADAS, McGinn

18. Discussion • Addition of new search terms? • Acceptable level missing articles? • Other available resources for literature? • Decide on quality guidelines

19. HRB Centre for Primary Care ResearchDepartment of General PracticeRCSI Medical School Developing an International Register of CPRs for Primary Care: Identifying an Optimal Strategy to Search the Literature Claire Keogh Quality Assessment of CPR studies Emma Wallace