Global Heart Valve Repair and Replacement Market - Size, Analysis, Trends and Share 2014 - 2020

1. Global Heart Valve Repair and Replacement Market - China and India are expected to be the fastest growing markets in the region Persistence Market Research Global Heart Valve Repair and Replacement Market is expected to reach USD 4,712.7 million by 2020 - Persistence Market Research Persistence Market Research 1

2. Global Heart Valve Repair and Replacement Market - China and India are expected to be the fastest growing markets in the region Persistence Market Research Released New Market Report “Global Market Study on Heart Valve Repair and Replacement: Asia Pacific to Witness Highest Growth by 2020,” the global heart valve repair and replacement market was valued at USD 2,945.2 million in 2014 and is expected to grow at a CAGR of 8.1% from 2014 to 2020, to reach USD 4,712.7 million by 2020. The global heart valve repair and replacement market is witnessing significant growth due to growing geriatric population, change in lifestyles, and associated conditions leading to cardiovascular disorders. Moreover, technological advancements in the heart valve repair and replacement devices and surgeries, and rise in medical tourism promoting heart valve repair and replacement surgeries are also driving the market. However, there are various risks and complications associated with heart valve repair and replacement surgeries such as irregular heart rhythm, breathing problem, and embolism. Furthermore, lack of primary healthcare infrastructure in developing countries inhibits the growth of the heart valve repair and replacement market. The heart valve repair and replacement market is anticipated to grow from an estimated USD 2,945.2 million in 2014 to USD 4,712.7 million by 2020 at a CAGR of 8.1% during the forecast period. Request Customize Full TOC: http://www.persistencemarketresearch.com/toc/3192 In North America, the prevalence of cardiovascular diseases is high compared to other regions of the world due to increasing rate of obesity and change in lifestyle in the region. In the U.S., approximately 70,000 heart valve procedures are performed for mitral valve stenosis annually. In Europe, the heart valve repair and replacement market is driven by a rise in geriatric population, increasing the prevalence of lifestyle-associated disease, and change in lifestyles. Cardiovascular diseases cause more deaths among Europeans Approximately 50,000 valve replacement surgeries take place annually. Persistence Market Research 2

3. Global Heart Valve Repair and Replacement Market - China and India are expected to be the fastest growing markets in the region However, the growth of heart valve repair and replacement market in Asia Pacific is much higher than that in developed countries due to the large population base, change in lifestyles, increasing prevalence of lifestyle associated diseases, and rising medical tourism in the region. Request Sample Report: http://www.persistencemarketresearch.com/samples/3192 Edwards Lifesciences Corporation, St. Jude Medical, Inc., Medtronic, Inc., Sorin Group, Boston Scientific Corporation, and Abbott Laboratories, Inc. are some of the major players in the heart valve repair and replacement market. Buy Full Report: http://www.persistencemarketresearch.com/market-research/heart-valve- repair-replacement-market.asp The heart valve repair and replacement market is segmented as follows: By type of procedure Heart valve repair • Heart valve replacement • By type of replacement Tissue heart valve • Transcatheter heart valve • Mechanical heart valve • Persistence Market Research 3

4. Global Heart Valve Repair and Replacement Market - China and India are expected to be the fastest growing markets in the region By geography North America The U.S. • Europe Germany • France • Spain • The U.K. • Asia China • Japan • India • Rest of the World (RoW) Persistence Market Research 4

5. Global Heart Valve Repair and Replacement Market - China and India are expected to be the fastest growing markets in the region Market History: The global heart valve repair and replacement market is witnessing significant growth due to growing geriatric population, change in lifestyles, and associated conditions leading to cardiovascular disorders. Moreover, technological advancements in heart valve repair and replacement devices and surgeries, and rise in medical tourism promoting heart valve repair and replacement surgeries are also driving the market. However, there are various risks and complications associated with these surgeries such as irregular heart rhythm, breathing problems, and embolism. Furthermore, lack of primary healthcare infrastructure in developing countries inhibits the growth of the heart valve repair and replacement market. The heart valve repair and replacement market is anticipated to grow from an estimated USD 2,945.2 million in 2014 to USD 4,712.7 million by 2020 at a CAGR of 8.1% during the forecast period. North America was the largest market for heart valve repair and replacement in 2014, with tissue heart valve being the most popular type of heart valve replacement. In terms of growth, Asia Pacific is the fastest growing region. In terms of type of valve, while transcathater heart valve was the fastest growing segment. Heart valve repair is the repair of the damaged leaflet tissue, and resizing of the heart valve by removing excessive tissue. The global heart valve replacement market is expected to grow from an estimated USD 2,281.2 million in 2014 to USD 3,767.0 million in 2020 at a CAGR of 8.7% during the forecast period. Persistence Market Research 5

6. Global Heart Valve Repair and Replacement Market - China and India are expected to be the fastest growing markets in the region Table of Content Chapter 1 Preface 1.1 Report Description 1.2 Research Methodology 1.3 Assumptions Chapter 2 Market Synopsis Chapter 3 Porter’s Five Forces Analysis 3.1 Bargaining Power of Suppliers 3.2 Bargaining Power of Buyers 3.3 Threat of New Entrants 3.4 Threat of Substitutes 3.5 Intensity of Rivalry Chapter 4 Industry Overview 4.1 Market Definition 4.2 Market Drivers 4.2.1 Growing geriatric population 4.2.2 Changing lifestyles and associated conditions leading to cardiovascular disorders 4.2.3 Rise in medical tourism 4.2.4 Technological advancements in heart valve repair and replacement surgeries and devices 4.3 Impact Analysis of Market Drivers 4.4 Market Restraints 4.4.1 Risks and complications associated with heart valve repair and replacement surgeries 4.4.2 Lack of primary healthcare infrastructure in developing countries 4.5 Impact Analysis of Market Restraints 4.6 Market Trends 4.6.1 Growing product innovation Chapter 5 Global Market Size and Forecast Persistence Market Research 6

7. Global Heart Valve Repair and Replacement Market - China and India are expected to be the fastest growing markets in the region Chapter 6 Market Size and Forecast by Type of Procedure 6.1 Heart Valve Repair 6.2 Heart Valve Replacement Chapter 7 Market Size and Forecast by Type of Replacement 7.1 Mechanical Heart Valve 7.2 Tissue Heart Valve 7.3 Transcathater Heart Valve Chapter 8 Market Size and Forecast by Geography 8.1 North America 8.2 Europe 8.3 Asia Pacific Chapter 9 Competitive Scenario 9.1 Company Share Analysis Chapter 10 Company Profiles 10.1 Edwards Lifesciences Corporation (Edwards) 10.1.1 Company overview 10.1.2 Products and services 10.1.3 Financial performance 10.1.4 Key developments 10.2 St. Jude Medical, Inc. 10.2.1 Company overview 10.2.2 Products and services 10.2.3 Financial performance 10.2.4 Key developments 10.3 Sorin Group 10.3.1 Company overview 10.3.2 Products and services 10.3.3 Financial performance 10.3.4 Key developments 10.4 Boston Scientific Corporation 10.4.1 Company overview Persistence Market Research 7

8. Global Heart Valve Repair and Replacement Market - China and India are expected to be the fastest growing markets in the region 10.4.2 Products and services 10.4.3 Financial performance 10.4.4 Key developments 10.5 Medtronic, Inc. 10.5.1 Company overview 10.5.2 Products and services 10.5.3 Financial performance 10.5.4 Key developments 10.6 CryoLife, Inc. 10.6.1 Company overview 10.6.2 Products and services 10.6.3 Financial performance 10.6.4 Key developments 10.7 Colibri Heart Valve, LLC 10.7.1 Company overview 10.7.2 Products and services 10.7.3 Financial performance 10.7.4 Key developments 10.8 Abbott Laboratories, Inc. (Abbott) 10.8.1 Company overview 10.8.2 Products and serices 10.8.3 Financial performance 10.8.4 Recent developments 10.9 On-X Life Technologies, Inc. 10.9.1 Company overview 10.9.2 Products and services 10.9.3 Financial performance 10.9.4 Key developments 10.10 Neovasc, Inc. 10.10.1 Company overview 10.10.2 Products and services 10.10.3 Financial performance 10.10.4 Key developments Persistence Market Research 8

9. Global Heart Valve Repair and Replacement Market - China and India are expected to be the fastest growing markets in the region List of Tables TABLE 1 Market snapshot: heart valve repair and replacement market, 2014 and 2020 TABLE 2 Types of heart valves TABLE 3 Cost of heart valve replacement surgery in various countries TABLE 4 Drivers for heart valve repair and replacement market: Impact analysis TABLE 5 Restraints for global heart valve repair and replacement market: Impact analysis TABLE 6 Some of the products launched by various companies TABLE 7 Global heart valve repair and replacement market size, by region, 2010 – 2013 (USD million) TABLE 8 Global heart valve repair and replacement market size, by region, 2014 – 2020 (USD million) TABLE 9 Global heart valve repair and replacement market size, by type of procedure, 2010 – 2013 (USD million) TABLE 10 Global heart valve repair and replacement market size, by type of procedure, 2014 – 2020 (USD million) TABLE 11 Global heart valve repair and replacement market size, by type of replacement, 2010 – 2013 (USD million) TABLE 12 Global heart valve repair and replacement market size, by type of replacement, 2014 – 2020 (USD million) TABLE 13 Global heart valve repair market size, by region, 2010 – 2013 (USD million) TABLE 14 Global heart valve repair market size, by region, 2014 – 2020 (USD million) TABLE 15 Global heart valve replacement market size, by region, 2010 – 2013 (USD million) TABLE 16 Global heart valve replacement market size, by region, 2014 – 2020 (USD million) TABLE 17 Global mechanical heart valve market size, by region, 2010 – 2013 (USD million) TABLE 18 Global mechanical heart valve market size, by region, 2014 – 2020 (USD million) TABLE 19 Global tissue heart valve market size, by region, 2010 – 2013 (USD million) TABLE 20 Global tissue heart valve market size, by region, 2014 – 2020 (USD million) TABLE 21 Global transcathater heart valve market size, by region, 2010 – 2013 (USD million) TABLE 22 Global transcathater heart valve market size, by region, 2014 – 2020 (USD million) TABLE 23 The North American heart valve repair and replacement market size, by country, 2010 – 2013 (USD million) TABLE 24 The North American heart valve repair and replacement market size, by country, 2014 – 2020 (USD million) Persistence Market Research 9

10. Global Heart Valve Repair and Replacement Market - China and India are expected to be the fastest growing markets in the region TABLE 25 The European heart valve repair and replacement market size, by country, 2010 – 2013 (USD million) TABLE 26 The European heart valve repair and replacement market size, by country, 2014 – 2020 (USD million) TABLE 27 The Asia Pacific heart valve repair and replacement market size, by country, 2010 – 2013 (USD million) TABLE 28 The Asia Pacific heart valve repair and replacement market size, by country, 2014 – 2020 (USD million) TABLE 29 Major products segments of Edwards Lifesciences Corporation TABLE 30 Major products segments of St. Jude Medical, Inc TABLE 31 Major products segments of Sorin Group TABLE 32 Major products segments of Boston Scientific Corporation TABLE 33 Major products segments of Medtronic, Inc. TABLE 34 Major products segments of CryoLife, Inc. TABLE 35 Major products segments of Colibri Heart Valve, LLC TABLE 36 Major products segments of Abbott Laboratories, Inc. TABLE 37 Major products segments of On-X Life Technologies, Inc. TABLE 38 Major products segments of Neovasc, Inc. List of Figures FIG. 1 Heart valve repair and replacement market: Porter’s five force analysis FIG. 2 Cardiac cycle FIG. 3 Types of heart valve procedure FIG. 4 Aging population in major regions, 2000 – 2050 (% share in total population) FIG. 5 Prevalence of overweight or obese males aged 30 years and above, 2005 and 2015, (%) FIG. 6 Prevalence of overweight or obese females aged 30 years and above, 2005 and 2015 (%) FIG. 7 Global heart valve repair and replacement market share, by region, by value, 2013 FIG. 8 Global heart valve repair and replacement market share, by type of procedure, by value, 2013 FIG. 9 Global heart valve repair and replacement market share, by type of replacement, by value, 2013 FIG. 10 Global heart valve repair and replacement market share, by region, by value, 2013 Persistence Market Research 10

11. Global Heart Valve Repair and Replacement Market - China and India are expected to be the fastest growing markets in the region FIG. 11 Global heart valve replacement market share, by region, by value, 2013 FIG. 12 Global mechanical heart valve market share, by region, by value, 2013 FIG. 13 Global tissue heart valve market share, by region, by value, 2013 FIG. 14 Global transcathater heart valve market share, by region, by value, 2013 FIG. 15 The North American heart valve repair and replacement market share, by country, by value, 2013 FIG. 16 The European heart valve repair and replacement market share, by country, by value, 2013 FIG. 17 The Asia Pacific heart valve repair and replacement market share, by country, by value, 2013 FIG. 18 Company share of the heart valve repair and replacement market FIG. 19 Net sales and net income of Edwards Lifesciences Corporation, 2012 – 2014 (USD million) FIG. 20 Net sales and net income of St. Jude Medical, Inc., 2012 – 2014 (USD million) FIG. 21 Net revenue and net profit of Sorin Group, 2011 – 2013 (USD million) FIG. 22 Net sales and net income of Boston Scientific Corporation, 2012 – 2014 (USD million) FIG. 23 Net sales and net earnings of Medtronic, Inc., 2012 – 2014 (USD million) FIG. 24 Revenue and net income of CryoLife, Inc., 2012 – 2014 (USD million) FIG. 25 Abbott net sales and net earnings, 2011 – 2013 (USD million) FIG. 26 Revenue and net income/loss of Neovasc, Inc., 2011 – 2013 (USD million) About Us: Persistence Market Research (PMR) is a full-service market intelligence firm specializing in syndicated research, custom research, and consulting services. PMR boasts market research expertise across the Healthcare, Chemicals and Materials, Technology and Media, Energy and Mining, Food and Beverages, Semiconductor and Electronics, Consumer Goods, and Shipping and Transportation industries. The company draws from its multi-disciplinary capabilities and high-pedigree team of analysts to share data that precisely corresponds to clients’ business needs. PMR stands committed to bringing more accuracy and speed to clients’ business decisions. From ready-to-purchase market research reports to customized research solutions, PMR’s engagement models are highly flexible without compromising on its deep-seated research values. Persistence Market Research 11

12. Global Heart Valve Repair and Replacement Market - China and India are expected to be the fastest growing markets in the region Contact Us: Persistence Market Research 305 Broadway 7th Floor, New York City, NY 10007, United States, USA - Canada Toll Free: 800-961-0353 Email: sales@persistencemarketresearch.com Web: http://www.persistencemarketresearch.com Persistence Market Research 12