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A Risk-Benefit Analysis of the use of NSAIDs in the Management of Arthritis

Risk of GI Complications and Death With Nonspecific NSAIDs . GI Ulcers/Bleeding/Perforation (FDA Data) : 1% patients = 6 months of NSAID use2-4% patients = I year of NSAID use103,000 hospitalizations and 16,500 deaths annually related to nonspecific NSAID use (Wolfe et al. N Engl J Med 1999).

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A Risk-Benefit Analysis of the use of NSAIDs in the Management of Arthritis

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    1. A Risk-Benefit Analysis of the use of NSAIDs in the Management of Arthritis Anne-Barbara Mongey, MD, DCH, MRCPI Associate Professor of Internal Medicine University of Cincinnati

    2. Risk of GI Complications and Death With Nonspecific NSAIDs GI Ulcers/Bleeding/Perforation (FDA Data) : 1% patients = 6 months of NSAID use 2-4% patients = I year of NSAID use 103,000 hospitalizations and 16,500 deaths annually related to nonspecific NSAID use (Wolfe et al. N Engl J Med 1999)

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