1 / 1

Kannan et al., 2002. Environmental Science and Technology 36, 3210-3216.

keona
Download Presentation

Kannan et al., 2002. Environmental Science and Technology 36, 3210-3216.

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Perfluorinated compounds in tuna (Thunnus thynnus) specimens fromMediterranean (Sardinia, Italy): levels and risks for human consumptionSimone Badini1, Cristiana Guerranti1 2, Monia Renzi3, Guido Perra1, Alessandro Cau4, Silvano Ettore Focardi11- Department of Physical, Earth and Environmental Sciences, University of Siena, Via Mattioli 4, 53100, Siena, Italy2- Institute of Clinical Physiology, National Research Council (CNR), Via Moruzzi, 1, 56100 Pisa, Italy3- Department of Biotechnology and Environmental Science, University of Salento, Ecotekne, Strada per Monteroni I-73100, Lecce, Italy4- Department of Life Science and Environment, University of Cagliari, via T. Fiorelli 1, 09126, Cagliari, ItalyE-mail contact: guerranticri@unisi.it Emerging pollutants, like perfluorinated compounds (PFCs), show bioaccumulation properties reported by many authors (e.g.: Kannan et al., 2002). While it’s well proved that the most important contribution to human PFCs intake is the diet, being fish and seafood the main contributors, (EFSA, 2011; Guerranti et al., 2013) The aim of this study was to assess the accumulation of two PFCs, perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), in the Atlantic bluefin tuna from the coasts of Sardinia (Tyrrhenian Sea). Furthermore, due to the importance of tuna for human consumption, the intake of PFCs through tuna consumption was estimated and compared with safe thresholds. 23 samples of muscle were excised from twenty-three Atlantic bluefin tuna (Thunnus thynnus) caught off the Western and Eastern coasts of Sardinia, North Western Mediterranean Sea. PFOS and PFOA were extracted using an ion-pairing extraction procedure and measured using high-performance liquid chromatography (HPLC) with electrospray ionisation (ESI) tandem mass spectrometry Since PFCs show toxicity and prolonged exposure can affect endocrine function and cause neurodevelopmental disorders and infertility (Iughetti et al., 2011; La Rocca et al., 2012; Caserta et al., 2013) we have calculated the estimated daily ingestion of the contaminants of interest through tuna consumption. We calculated the EDI for the general Italian population and for those who claimed to be fish consumers (Leclercq et al., 2009), assuming that their daily fish intake consisted solely of Atlantic bluefin Tuna fillets. In all cases considered, the estimated ingestion of toxic contaminants through tuna fillet consumption seems very far from posing any risk for humans, as the intakes of PFCs are very low. The results were elaborated relating the accumulation to the size and age and showed a correlation between the levels of PFOS and MEHP (results presented in another poster). PFOS was found, at low levels, while PFOA was never detected, confirming previous studies (Kannan et al., 2002; Guerranti et al., 2013); although the prevalence of PFOS on PFOA in animal, human and environmental samples is very diffuse, it is interesting to notice that this PFC has never been delectated in tuna (muscle or liver) and this leads to hypothesize a rapid metabolization of this compound in this fish and/or a very limited exposure. The estimated ingestion of the contaminants considered through tuna fillet consumption resulted very far from posing any risk for humans, confirming the great value of tuna fillet as food. On the other hand, concerning the health of the Atlantic bluefin tuna, particular attention should be paid to the accumulation of contaminants, because evidence of possible reproductive impairment due to the endocrine disrupting activity (Fossi et al., 2002) may be causes of concern for this species. Guerranti et al. (2013) report PFCs data on four samples of fresh tuna fillet purchased from a supermarket in central Italy: as well as in this study, the PFOA was always <LOD, while the PFOS had an average of 30.2±36.5 ng/g w.w., a median of 19.92 ng/g w.w.. Kannan et al. (2002) reported levels of contamination by PFCs in the liver of tuna sampled along the coasts of the Mediterranean (Calabria, Southern Italy); PFOS was present at concentrations between 21 and 87 ng /g w.w., while PFOA was never detected, as in the present study. Kannan et al., 2002. Environmental Science and Technology 36, 3210-3216. EFSA, 2011.EFSA Journal 9, 2016-2049. Guerranti et al., 2013. Food Chemistry 140, 197-203. Iughetti et al., 2011. Hormone Research In Paediatrics 76(S2), 57. La Rocca et al., 2012. International Journal of Hygiene and Environmental Health 215(2), 206-211. Caserta et al., 2013. International Journal of Endocrinology, Article ID 510703, 7 pages. Leclercq et al., 2009. Public Health Nutrition 12(12), 2504-2532.

More Related