DNA Damage, DNA Technologies, Genetics Since Gregor Mendel

DNA Damage, DNA Technologies, Genetics Since Gregor Mendel

11.15.2010 Catalyst: • What is the difference between genes and alleles? Please define each word, and give an example of each.

Standards and Objectives Standard: I.I.I.2. Use models to explain the relationships between variables being investigated. Content: SWBAT: compare predicted results with expected results in a lab Language: SWBAT Write a paragraph describing the results of the experiment

AGENDA: • CATALYST: • Opening: • INM: Explain Bean Lab • GP: Explain Math concepts • INP: Finish the lab and compare results • Exit Ticket: None • Closing: Hand in Lab Modeling Inheritance 11.15.2010

Opening = Black rabbit coat allele = Brown rabbit coat allele

Calculate Ratio:

11.16.2010 Catalyst:

Standards and Objectives Standard: III.I.I.1. Analyze the contributions of science to health as they relate to personal decisions about smoking, drugs, alcohol, and sexual activity. Content: SWBAT: analyze a situation involving drugs, alcohol, and smoking, from a scientific point of view. Language: SWBAT Explain in writing what drugs, alcohol, and smoking can do to your cells (DNA damage).

AGENDA: • CATALYST: • Opening: Montana Meth Project • INM: Notes about Drugs • GP: Explain scientific evidence • INP: Write a short answer question • Exit Ticket: Short answer • Closing: Hand in Lab DNA Damage, Scientific Information about DRUGS 11.16.2010

Opening

I. Drugs are substances that change normal bodily function Behavioral or physical

DRUGS DAMAGE DNADate: • Drugs are substances that change normal bodily function. • All of the following illegal drugs damage DNA (can harm the person and/or the offspring) • Can cause unconsciousness, vomiting, brain damage and death • Examples: alcohol, heroin, marijuana • Can cause seizures, headaches, paranoia, cancer, and death • Examples: caffeine* (not too bad for DNA), nicotine (cigarettes), cocaine • Can cause panic, feeling of losing touch with reality, nervous system damage, death • Examples: LSD, mushrooms, XTC • Using drugs now can shorten your lifespan. Summary:

II. All Illegal Drugs Damage DNA • Why is DNA damage bad?

DRUGS DAMAGE DNADate: • Drugs are substances that change normal bodily function. • All of the following illegal drugs damage DNA (can harm the person and/or the offspring) • Can cause unconsciousness, vomiting, brain damage and death • Examples: alcohol, heroin, marijuana • Can cause seizures, headaches, paranoia, cancer, and death • Examples: caffeine* (not too bad for DNA), nicotine (cigarettes), cocaine • Can cause panic, feeling of losing touch with reality, nervous system damage, death • Examples: LSD, mushrooms, XTC • Using drugs now can shorten your lifespan. Summary:

Types of Drugs, and What They Do to you. A. Depressants slow you down • cause unconsciousness, vomiting, brain damage and death • Examples: alcohol, heroin, marijuana

DRUGS DAMAGE DNADate: • Drugs are substances that change normal bodily function. • All of the following illegal drugs damage DNA (can harm the person and/or the offspring) • Depressants cause unconsciousness, vomiting, brain damage and death • Examples: alcohol, heroin, marijuana • Stimulants cause seizures, headaches, paranoia, cancer, and death • Examples: caffeine* (not too bad for DNA), nicotine (cigarettes), cocaine • Hallucinogens cause panic, feeling of losing touch with reality, nervous system damage, death • Examples: LSD, mushrooms, XTC • Using drugs now can shorten your lifespan. Summary:

Types of Drugs, and What They Do to you. B. Stimulants speed you up. • cause seizures, headaches, paranoia, cancer, and death • Examples: caffeine* (not too bad for DNA), nicotine (cigarettes), cocaine

Types of Drugs, and What They Do to you. Hallucinogens make you see and feel things that aren’t real. • cause panic, feeling of losing touch with reality, nervous system damage, death • Examples: LSD, mushrooms, XTC

III. Using drugs NOW can shorten your lifespan

GP: Think, Pair, Share 1. Melanie is at a club in the city. A stranger offers her some XTC. What scientific information could she use to help her make a decision about using this drug?

GP: Think, Pair, Share 2. Abraham is hanging out with some friends. A stranger approaches the group and offers them all some marijuana. What scientific evidence could Abraham tell his friends that could help them make this decision?

GP: Think, Pair, Share 3. Xavier is a miner in Chile. All of his co-workers use cocaine so they can stay awake in the mine and be less hungry. When he is offered cocaine, what scientific evidence could he use to help him make his decisions?

INP: 1. Frederick is hiking in the woods and finds some mushrooms. His friend tells him that eating these mushrooms will make him hallucinate. What scientific information could Frederick use to help him make a decision about using this drug?

INP: 2. A person is on a crowded street corner, where lots of people are taking a “cigarette break.” One of the person’s co-workers offers a cigarette to the person. What scientific information could the person use to help make a decision about using this drug?

Exit Ticket: • Bob sees many adults who use alcohol. He wants to make an informed decision about using alcohol. What scientific knowledge could Bob use to help him make his decision? • Elyse is offered tobacco. She wants to make an informed decision about using the drug. What scientific knowledge could she use to help her make the decision?

11.18.2010 Catalyst:

Standards and Objectives Standard: II.II.II.6. Know that hereditary information is contained in genes that are located in chromosomes, including: -determination of traits by genes -traits determined by one or many genes -more than one trait sometimes influenced by a single gene. Content: SWBAT: Explain that inherited traits can be caused by many genes. Explain that inherited traits (more than one) can be caused by one gene. Language: SWBAT make 3 versions of a cause-effect diagram

AGENDA: • CATALYST: • Opening: Eye Color Explanation • INM: Notes about Genetics • GP: Graphic Cause-Effect Organizers • INP: ACE Paragraph • Exit Ticket: Hand in ACE Paragraph • Closing: Cold Call Genetics After Gregor Mendel 11.18.2010

Opening: Eye color doesn’t follow Mendel’s rules. http://www.art-dept.com/artists/rankin/portfolio/specialprojects/eyescapes/portfolio.html

Opening: Eye color doesn’t follow Mendel’s rules.

Scientists found that genes do not always work like Mendel described. Mendel: One allele = one trait

Genetics Since G. Mendel Date: • Scientists found that genes do not always work like Mendel described. • More than one gene can cause one trait • Example: Eye color and height are caused by more than one gene. • More than one trait can be caused by one gene • Example: Chicken “Frizzle” disorder, Phenylketonuria (PKU) • The environment can play a role in gene expression • Example: Himalayan rabbits have genes that make their fur dark only at lower temperatures Summary:

A. More than one gene can cause one trait. Eye Color Human Height

Genetics Since G. Mendel Date: • Scientists found that genes do not always work like Mendel described. • More than one gene can cause one trait • Example: Eye color and height are caused by more than one gene. • More than one trait can be caused by one gene • Example: Chicken “Frizzle” disorder, Phenylketonuria (PKU) • The environment can play a role in gene expression • Example: Himalayan rabbits have genes that make their fur dark only at lower temperatures Note: Leave 6 lines of space before letter B Summary:

B. More than one trait can be caused by one gene. • Chicken “Frizzle” disorder • PKU

DNA Damage, DNA Technologies, Genetics Since Gregor Mendel