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Lecture 15 Regulatory variation and eQTLs

Lecture 15 Regulatory variation and eQTLs

6.047/6.878/HST.507 Computational Biology: Genomes, Networks, Evolution. Lecture 15 Regulatory variation and eQTLs. Chris Cotsapas cotsapas@broadinstitute.org. Module 4: Population / Evolution / Phylogeny. L15/16: Association mapping for disease and molecular traits

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705 views • 59 slides
The Identification of Human Quantitative Trait Loci

The Identification of Human Quantitative Trait Loci

The Identification of Human Quantitative Trait Loci. Dr John Blangero Southwest Foundation for Biomedical Research ChemGenex Pharmaceuticals. The Goals: Genetic Analysis of Complex Phenotypes. QTL Localization Where in the genome is the QTL located? QTL Identification

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687 views • 52 slides
Gene mapping in mice

Gene mapping in mice

Gene mapping in mice. Karl W Broman Department of Biostatistics Johns Hopkins University http://www.biostat.jhsph.edu/~kbroman. Goal. Identify genes that contribute to common human diseases. Inbred mice. Advantages of the mouse. Small and cheap Inbred lines Large, controlled crosses

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838 views • 45 slides
Gene mapping in mice

Gene mapping in mice

Gene mapping in mice. Karl W Broman Department of Biostatistics Johns Hopkins University http://www.biostat.jhsph.edu/~kbroman. Goal. Identify genes that contribute to common human diseases. Inbred mice. Advantages of the mouse. Small and cheap Inbred lines Large, controlled crosses

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457 views • 45 slides
All you need to know about QTLS

All you need to know about QTLS

All you need to know about QTLS. September 2019. Purpose of the session. To provide an overview of the QTLS process: What is professional formation and why apply? Stages, timescales and how to gain QTLS Eligibility and cost Collecting and collating your evidence Support available from SET

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244 views • 23 slides

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