1 / 3

epoxide hydrolase 1, microsomal (xenobiotic)

Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Allen339
Download Presentation

epoxide hydrolase 1, microsomal (xenobiotic)

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) BackgroundEpoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene. SynonymsEPHX1; epoxide hydrolase 1, microsomal (xenobiotic); EPHX; epoxide hydrolase 1; epoxide hydratase; MEH; EPOX; HYL1 Recombinant Proteins Cell & Tissue Lysates Cat.#Product name Source (Host) SpeciesTag Price EPHX1-22HRecombinant Human EPHX1 Protein, His-tagged Insect cellHuman His+Inquiry EPHX1-3407HRecombinant Human EPHX1 Protein, GST-taggedWheat GermHuman GST+Inquiry EPHX1-390H Recombinant Human EPHX1, MYC/DDK-tagged HEK293Human +Inquiry

  2. EPHX1-205H Recombinant Human EPHX1Mammalian Cells Human His+Inquiry EPHX1-28685TH Recombinant Human EPHX1Wheat germ Human +Inquiry EPHX1-463H Recombinant Human epoxide hydrolase 1, microsomal (xenobiotic), T7 taggedE. coliHuman T7+Inquiry EPHX1-5064HRecombinant Human EPHX1, T7-tagged E. coli Human T7+Inquiry EPHX1-5252MRecombinant Mouse EPHX1 ProteinMammalian CellsMouse His+Inquiry EPHX1-1486RRecombinant Rhesus monkey EPHX1 Protein, His-taggedMammalian Cells Rhesus Macaque His+Inquiry EPHX1-11294ZRecombinant Zebrafish EPHX1Mammalian CellsZebrafishHis+Inquiry Involved Pathway EPHX1 involved in several pathways and played different roles in them. We selected most pathways EPHX1 participated on our site, such as Metabolism of xenobiotics by cytochrome P, Bile secretion, Chemical carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPHX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

  3. Pathway NamePathway Related Protein Metabolism of xenobiotics by cytochrome PGSTM3; UGT1A3; UGT1A4; AKR7A5; UGT1A6; MGST2; ALDH3B1; HSD11B1; UGT2B7; GSTM2 Bile secretionABCB4; NCEH1; ATP1B2; SLCO1B2; CFTR; ADCY3; SLC4A4; GNAS; Slc4a2; SLC5A1 Chemical carcinogenesisMGST3; CYP2C37; CYP3A41A; UGT1A2; HSD11B1; CYP2C18; GSTO2; CYP2C19; GSTM3; GSTT1 Protein Function EPHX1 has several biochemical functions, for example, cis-stilbene-oxide hydrolase activity, epoxide hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EPHX1 itself. We selected most functions EPHX1 had, and list some proteins which have the same functions with EPHX1. You can find most of the proteins on our site. FunctionRelated Protein Function cis-stilbene-oxide hydrolase activityRelated Protein EPHX1 Function epoxide hydrolase activityRelated Protein EPHX3; EPHX4; RNPEP; EPHX2; Npepo; LTA4H; EPHX1

More Related