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Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

Cytoreductive surgery with Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is an advanced procedure for managing several types of cancer. Dr. Neeraj Goel perform cytoreductive surgery with HIPEC in Delhi.

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Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

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  1. CytoreductiveSurgeryWithHyperthermic IntraperitonealChemotherapy(HIPEC)InDelhi CytoreductiveSurgery WhatiscytoreductivesurgerywithHyperthermic IntraperitonealChemotherapy(HIPEC)? CytoreductivesurgerywithHyperthermicIntraperitonealChemotherapy(HIPEC) is anadvancedprocedureformanagingseveraltypesof cancer.The doctormay performtheprocedureinpatientswithabdominalcancerwhichhavespreadtoand limited totheinnerlining oftheabdomencalledperitoneum. Itoffersseveral advantages to the patients. It helps in delivering the drug at the site of action and improvestheoverallsurvivalrate.Lessamountofdrugissystemicallyabsorbed leadingto fewersystemic side effects. Howshould IknowthatIneedcytoreductive surgery with HyperthermicIntraperitonealChemotherapy(HIPEC)?

  2. YourdoctorwillrecommendyoutoundergocytoreductivesurgerywithHIPECifyou aresufferingfromcancersoftheabdominalcavity.Cytoreductivesurgerywith HIPECis usedto metastaticcancers ofthecolon,rectum,ovary andstomach. It is alsousedforthetreatmentofperitonealmesothelioma,pseudomyxomaperitonei andotherdisorders.Itisimportant toaccuratelydiagnosetheperitoneal malignancies. • Whatisthe procedure for performingcytoreductive surgerywithHyperthermic Intraperitoneal Chemotherapy(HIPEC)? • The procedure ofcytoreductivesurgerywithHIPECis oftwo steps.Inthe firststep, the doctorsperformcytoreductivesurgery.Duringthis procedure,theGI • surgeonremovesthevisiblecanceroustissuesandleavesthemicroscopictissues. Apart from the tissues, the surgeon may also remove the organ or part of an organ if itis notpossibletoremovethecanceroustissues.Thedoctormayremoveorgans such asthegallbladder,sectionofthesmallorlargeintestine,andspleen. • ThedoctorthenperformsHyperthermicIntraperitonealChemotherapy (HIPEC)to • remove the microscopic cancerous cells. The surgeon heats the chemotherapeutic drug and delivers them directly into the abdominal cavity through the catheter. The heating temperature is around 42-43°C. The cancerous cells die at 40°C, while the normalhealthy cellsdie at 44°C. • What aretheadvantagesofcytoreductive surgery with HyperthermicIntraperitonealChemotherapy (HIPEC)? • CytoreductivesurgerywithHIPECisanadvancedprocedureforseveraltypesof cancers.ItcombinestheadvantagesofbothcytoreductivesurgeryandHIPEC. • One of thecommon advantages of thissurgeryinclude: • Highdrugpermeation:Thisprocessresultsin high drugpermeationintothecancerous • tissues.Thetechniqueinvolvesthe deliveryofthe chemotherapeuticdrugdirectlyinto the abdominal cavityto achievemaximumefficacy. • Improvementinoverallsurvival:Severalstudieshave been performedon thesurvivalof • patientswith peritonealcancerafter cytoreductivesurgerywithHIPEC. Mostofthestudies indicate thatthistechnique improvesthe overallsurvivalrate.In astudydone on peritoneal

  3. metastasesfromcolorectalcancer,themediansurvivalwassignificantlyhigherascompared tosurgeryandchemotherapy,onlysurgery,chemotherapyonly,and bestsupportivecare. • Treatschallengingcancers:CytoreductivesurgerywithHIPEChasgiven hope for patients • sufferingfromcancersthat areverychallengingto manage.Itisimportantto notethatthe cancer tissuesresidingon thesurfaceofthe abdominalorgansorwallsaredifficult to treat withintravenouschemotherapy. • Significantreductionincanceroustissues:CytoreductivesurgerywithHIPECtargetsthe • canceroustissuesthroughdifferentactionsandsignificantlyreduces theoverallcancerous tissues.Itresultsin delayed progression ofcancerinto theadvanced stageand improves survival. • What arethe risks associatedwithcytoreductivesurgery withHyperthermicIntraperitonealChemotherapy (HIPEC)? • ThereareseveralrisksassociatedwithcytoreductivesurgerywithHIPEC.Someof themare: • Clot formation:Patientswith thistechniqueareatincreasedriskfor developing theclotthat • maytraveltovitalorgansand mayleadtolife-threateningcomplications. • Riskof infection:Duetothe exposure ofthe internaltissues,the patientsareatriskfor developinganinfection. • Cardiovascularcomplications:HIPECresultsinraising thetemperature to 40.5°C.Itmay • resultincardiovascularalterationssuchasincreased heartrate,peripheralvasodilation, low cardiacoutput,andreductioninsystemicvascularresistance. • Whichdoctorwill performthecytoreductivesurgery with HyperthermicIntraperitonealChemotherapy(HIPEC)? • InDelhi? • Severaldoctorsperformcytoreductivesurgery with HIPECinDelhi.However,the efficacyand outcomeoftheproceduredependuponseveralfactors,includingthe • experienceofthedoctor,post-procedurecare,andthetypeofmedicalequipment andfacilitiesavailableatthehospital.ThepatientshouldconsultthebestGIsurgeon in DelhiforundergoingcytoreductivesurgerywithHIPEC inDelhi.

  4. Arethereoptimumfacilitiesavailableforcytoreductive surgerywithHyperthermicIntraperitoneal Chemotherapy(HIPEC)inDelhi? SeveralhospitalshavethefacilitiesforperformingcytoreductivesurgerywithHIPEC inDelhi.ThebestGIsurgeonsinDelhiareassociatedwithsuper-specialty hospitalsinDelhiforperformingthisprocedure.Youshouldcheckforthefacilities available at thehospitalsinDelhibeforeoptingforthisprocedure. HowmanydaysdoIneedtostay for cytoreductive surgerywithHyperthermic Intraperitoneal Chemotherapy(HIPEC)inDelhi? CytoreductivesurgerywithHIPECinDelhitakesaround8-14hourstocomplete.The patienthadtoremaininthehospitalforaround7-10daysor more,dependingupon the typeofcancer.Thehealthcareteamadvisesthepatienttomaintainabalance betweenrestandactivityasbothareimportant.Whilethepatientmayfeelfatigued forabout2-3months,takingexcessiverestincreasestheriskofbloodclotformation. WhatshouldIdo IfIrequiremoredetailedinformation aboutcytoreductive surgerywithHyperthermic IntraperitonealChemotherapy(HIPEC)inDelhi? Cytoreductivesurgeryisamajorprocedureand isnotforeverypatientwith peritonealmesothelioma.Youmay have several questions toask yourdoctor regardingtheprocedure.Youmayfilltheformtogetyourqueriessolvedbythebest GIsurgeoninDelhi.

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