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Preventing Healthcare Associated Infections. W. Charles Huskins, MD, MSc Associate Professor, Pediatrics Mayo Clinic. Small things, done well together, can make a big difference. Objectives. Identify risk factors for central line infections
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Preventing Healthcare Associated Infections W. Charles Huskins, MD, MSc Associate Professor, Pediatrics Mayo Clinic
Objectives • Identify risk factors for central line infections • Describe practice strategies for line infection prevention • Review hand washing technique
Minnesota Health Care Quality Measures – Statewide Quality Report - 2010 Report http://www.health.state.mn.us/healthreform/measurement/report/index.html
Intraluminal Extraluminal Garland JS, et al. Infect Control Hosp Epidemiol 2008; 29:243-9
Preventative Intervention: Scrub the Hub • Scrub all injection caps for 15 seconds prior to accessing • Peripheral and central lines (adult/pediatric/neonate) • Use alcohol wipe • Allow to dry • Before blood draws, infusions, flushes…anytime the catheter is accessed
PICU Interventions • Improve facilities for hand hygiene • Use 2% chlorhexidine for line insertions for all patients >1kg or >14 days old • Reduce central line entries • Advance enteral feedings more quickly • Reduce unnecessary laboratory tests • Convert IV to po medications • Switch from bolus to continuous sedation if appropriate • Reprogram pumps to administer prn doses of medications
Children’s Hospital-Wide Intervention • Continue to emphasize • Insertion bundle • Standard maintenance practices – dressing change, hub change, administration set change • Daily assessment of need for line, promptly remove unneeded lines • Additional efforts to prevent contamination during line entry
Central Line Entry Bundle • Emphasize that line entry is a invasive procedure • Combine several interventions that can work together to reduce risk • Improve disinfection of hub • Reduce likelihood of contamination of hub • Reduce unnecessary line entry • Integrate into/redesign line entry workflow to reinforce adherence • Pilot test new devices to disinfect and protect hub from contamination
Standard Precautions andStrict Isolation to Prevent Spread of Clostridium difficile and Antimicrobial Resistant Bacteria
Environmental Cleaning with Bleach • Bleach wipes used daily • Clean all surfaces: • Crib hand rails & bars and bassinets surfaces • Door handles • Light switches • Tray tables • Bathroom sink handles • Additional forgotten surfaces: • Computer keyboards • Telephones
Interventions to Prevent Healthcare Associated InfectionsSmall things, done well together, can make a big difference • CLABSI • Reduce line entries • Scrub the hub • Protect the hub • Remove line whenit is no longer needed or convert to a lower risk line • Standard & Isolation Precautions • Wash hands upon entry in the ICU • Place and use hand rub at the point of care • Give direct feedback on compliance • Use bleach wipes for environmental cleaning
Definitions Catheter-associated urinary tract infection • Symptomatic infection • Asymptomatic bacteriuria
Pathophysiology Maki DG & Tambyah PA. Engineering out the risk with urinary catheters. Emerg Infect Dis 2001;7:342.
Log colony forming units / ml Days Bacteriuria and Urinary Catheters Maki DG & Tambyah PA. Engineering out the risk with urinary catheters. Emerg Infect Dis 2001;7:342.
Duration of Catheterization Daily Prevalence of Bacteriuria Garibaldi et al. Factors predisposing to bacteriuria during indwelling uretheral catheterization. N Engl J Med 1974;291:215.
Alternatives to Indwelling Urinary Catheters • Intermittent catheterization • Diapers • External bag collectors (infants & children) • Condom catheters
Catheter Insertion • Catheters should be inserted by trained personnel • Wash hands before insertion, preferably with an agent with antimicrobial activity • Clean the periurethral area and apply an antiseptic • Use a sterile catheter and drainage system • Use aseptic technique
Closed Sterile Drainage • 26% of catheters disconnected at some time • Risk of infection the day after disconnection was 2 times the risk if there was no disconnection Platt et al. Reduction of mortality associated with nosocomial urinary tract infection. Lancet 1983;I:893.
Closed Sterile Drainage Platt et al. Reduction of mortality associated with nosocomial urinary tract infection. Lancet 1983;I:893.
Care of Indwelling Urinary Catheters • Maintain a closed sterile drainage system • Monitor for obstruction of urinary flow • Inspect for encrustations • Maintain the drainage reservoir below the level of the bladder • Use individual containers to empty drainage reservoirs • Wash hands before and after touching the catheter or the drainage system