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Integrated Medical Systems, Inc.

Transforming Critical Care TM. Integrated Medical Systems, Inc. November 2013. Company. Vision – Transforming healthcare by dramatically empowering the caregiver Designs, manufactures, sells and services multi-function fully integrated patient care systems

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Integrated Medical Systems, Inc.

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  1. Transforming Critical Care TM Integrated Medical Systems, Inc. November 2013

  2. Company • Vision – Transforming healthcare by dramatically empowering the caregiver • Designs, manufactures, sells and services multi-function fully integrated patient care systems • Supplying U.S. and international military medical communities since 1998 • Transitioning from military to commercial • Every major award in the industry 2

  3. Corporate History 1994 – Established as the Advanced Biomedical Technology (ABT) group within Northrop Grumman 1999 – Northrop Grumman sold ABT unit to American Industrial Acquisition Corporation (AIAC) in exchange for: Working Capital line-of-credit commitment of up to $2.5M from AIAC 20% Preferred stake in IMS for NGC AIAC: privately-held conglomerate of primarily industrial commodities 3

  4. Management Team Bios Todd Kneale President / COO Founder / Patent Holder United Nations Tech Awards Stealth Bomber (Northrop) BSAE (Univ. of Michigan) David Cryer CFO Multiple high tech companies (Flight Safety Technologies, Trans Technology Corp) Government contracts expert B.S. Accounting (U-Mass) MBA (Ball State) • Matthew Hanson • VP – Sales • Founder • Merrill Lynch Innovation Grant • Stealth Bomber (Northrop) • GPS (Air Force) • Ph.D. (USC) • MBA (Chapman) • Frank Goodman • VP – Engineering • High reliability software (Intel, Trillium) • PhD (in process) Design Theory & Methods (UC-Berkeley) 4

  5. Board of Advisors - Commercial • Demetrios Demetriades, MD • Current - Chief of Trauma and Surgical Intensive Care, Los Angeles County+USC Medical Center • Former – Ran the world’s largest trauma center in South Africa • Michael Hernandez • Current – Founder and Chairman, Cova Corporation • Former – CEO, Wells Fargo Securities, LLC • Richard Martin, Ph.D. • Current – Medical device industry consultant • Former – President, Medtronic Physio-Control • Albert Myers • Current – Technology industry consultant • Former – Treasurer, Northrop Grumman Corporation • Adam Seiver, MD • Current – Chief Medical Officer, Respironics • Former – Director of Critical Care, Stanford University Medical Center 5

  6. Board of Advisors - Military • Ron Blanck, DO • Current – Partner, Martin Blanck & Associates // Former – Surgeon General of the U.S. Army • Paul Carlton, MD • Current – Director, Office of Homeland Security, Texas A&M Health Science Center // Former – Surgeon General of the U.S. Air Force • James Johnson, MD • Current – Senior Consultant // Former – Medical Officer of the U.S. Marine Corps • Harold Koenig, MD • Current – Chairman, Annapolis Center for Science-Based Public Policy // Former – Surgeon General of the U.S. Navy • John Parker, MD • Current – Senior Vice President, Health Solutions Center, SAIC // Former – Commander, U.S. Army Medical Research Materiel Command • James Peake, MD • Recent – Secretary of Veterans Affairs // Former – Surgeon General of the U.S. Army • Charles Roadman, MD • Recent – President, American Health Care Association // Former – Surgeon General of the U.S. Air Force • James Roudebush, MD • Current – Martin Blanck Associates // Recent – Surgeon General of the U.S. Air Force • Hugh Scott, DO • Current – Senior Medical Officer, Information Technology Sector, Northrop Grumman Corporation // Former – Navy Admiral in charge of Navy medical R&D • Robin Short, MD • Current – Operations Director, Planning and Healthcare Consultants, Ltd. // Former – Surgeon General of the UK Ministry of Defense 6

  7. Systems Integration - Defined • The art and science of combining multiple pieces of equipment into one…e pluribus unum! • Benefits include • Increased safety, ease-of-use, portability, reliability, maintainability, customizability, upgradeability, situational awareness, data continuity • Reduced weight, volume, cost and clutter 7

  8. Systems Integration - Applied • Apple • Combines phone, media player, camera, video camera, photo album, compass, GPS, calculator, map, etc. into ONE product • Enhances UI / UX • Added Apps that create capabilities not possible with discrete devices • In sum • Unclutters your space • Centralizes data display and storage, power and packaging • Reduced weight and volume of devices • Makes accessing, storing, using and sharing information more natural • IMS • Combines multiple diagnostic and therapeutic devices into ONE product • Enhancing UI / UX • Adding Apps that create capabilities not possible with discrete devices • In sum • Unclutters caregivers’ space • Centralizes data display and storage, power and packaging • Reduced weight and volume of devices • Makes accessing, storing, using and sharing information more natural 8

  9. The Problem • Information Overload • Loss of Vigilance • Conflicting Alarms • Clutter of Equipment • Weight • Volume • Damage • Loss • Spaghetti of Cables and Lines • Incl. too many power plugs, not enough outlets! • Patient Disconnect / Reconnect 9

  10. Problem = Opportunity • Multiple market segments combined represent a Total Market of $2B • “Smart beds” and data management tools = ultimate value equation for these technologies • Potential to dramatically reduce hospital design, construction, operation, maintenance and upgrade costs • Initial target market is in-hospital patient transport • Plagued with well-documented risks to patients and caregivers • No significant competitive barriers. • Revenue potential on the order of $50M by 2017 • Expand product line • Traditional market segments including the ICU and OR segments • Clinics, nursing homes, homecare, and future hospital construction models • Revenue Model • Sell capital equipment with related on-going revenue stream from disposables, consumables, training, extended warranties, maintenance, repairs, and upgrades 10

  11. The Solution =Medical Advanced Information Architecture (MAIA) • MAIA Provides Customizable Continuous Care for Multiple Broad and Niche Market Segments • Multiple medical devices from leading manufacturers, data systems and utilities all “modularized” and connected by • Common Data Bus • Common Power Bus • Common Structure • Benefits include • Safety (Situational Awareness, Remote Control…real telemedicine) • Ease-of-Use (Standardized, Reliable, Portable) • Modularity (Highly Customizable, Upgradeable, Maintainable) • Affordability (Revenue Generation, Cost-Savings/Avoidance) 11

  12. The Solution =Modular Subsystems POWER MANAGEMENT DATA COMMAND, DISPLAY, STORAGE, LOGGING VITAL SIGNS MONITOR VENTILATOR INFUSION PUMP FLUID WARMER DATA NETWORKING 12

  13. The Solution =Enhanced UX Status Quo * Inaccessible Data * Inaccessible Equipment * “Spaghetti” of Lines * Audio / Visual Data “Overload” * Equipment Clutter New User Experience * Accessible Data * Accessible Equipment * No “Spaghetti” of Lines * Audio / Visual Data and Control at Fingertip * No Equipment Clutter 13

  14. The Solution =Enhanced Information Management LSTAT Handheld Handheld / PDA Nurse’s Station Closed Loop Control Patient Record Systems Clinical Display Systems Telemedicine 14

  15. The Solution = Data without Borders * Embedded Mentoring / Training * Closed-Loop Control * Remote Control * Derived Parameters * Decision Support * Vigilance 15

  16. The Solution =Transforming Healthcare Facilities • “If the complexities of the building could be transferred to the bed…reducing the cost of hospital buildings and their subsequent renovations…The LSTAT Integrated Platform demonstrates that the technologies...are either currently available or under development” (Rice University Building Institute 2009) • Transition data management infrastructure from WLAN to cellular network • Multiple industries will press for more data, more realtime visibility, more interoperability from their smartphone/pads…3G  4G  TBD-G • Alerting • Vigilance • Cloud and Direct Access • Training • Already being implemented in emerging nations IMS ‘Smart Bed’ Mockup in CareStudio Prototype Suite at 2010 Health Care Facilities Expo 16

  17. The Solution =Sustainable Advantage • Smarter Systems through Software • Professional Apps • Enhanced UI/UX • Decision-Support • Closed-Loop Control • Data Analysis Tools • More Capable Systems through Hardware • Cellular vs. WLAN • Wireless Sensors • Oxygen Concentrator • New Battery Technology • New Materials Technology • New Circuit technology 17

  18. The LSTAT Patient Care Platform • State of the Art, FDA-cleared, Patented, Award-winning Trauma Patient Care Platform • Developed from 1994-1998 • FDA-cleared in 1998 • Sales from 1998 - 2008 Integrated Critical Care Capable Lightweight & Compact Self-Contained Ventilator – Physiological Monitor – 3-Channel Infusion Pump – Defibrillator – Blood Chemistry Analyzer – Suction Wired / Wireless (802.11) Communication – 72 Hours Continuous Data Storage – Secondary Display (handheld) On-Board Batteries – On-Board Oxygen (480 L) – Accepts Off-Board Power and Oxygen FDA Cleared - CE Mark Cleared - Export Cleared - Airworthiness Cleared 18

  19. LSTAT: Land, Air and Sea 19

  20. Dramatic Benefits Los Angeles County + University of Southern California Medical Center LSTAT Study Journal of the American College of Surgeons (2004) Physicians Needed During Transport “Time to Go” (Minutes) Rapid Patient Transfer Only One Physician Needed Prompt Discovery of Adverse Events Length of Stay (Days)1 Faster Vital Signs Awareness Shorter Length of Stay (1) Length of stay observed but not statistically demonstrated. 20

  21. Current Product – LS-1 • FDA cleared • Remotely-controllable • Ideal for non-trauma critical care patients • Lightweight, compact • Patents pending • Award-winning Ventilator – Physiological Monitor – Up to 5 Infusion Channels – Fluid Warmer Centralized Control and Display – Remote Control and Display - Wired / Wireless (802.11) Communication – >72 Hours Continuous Data Storage – Secondary Display (handheld) Hot-Swappable Batteries – Accepts Off-Board Power and Oxygen FDA Cleared -CE Mark Cleared - Export Cleared - Airworthiness Cleared (fall 2010) 21

  22. International ValidationAwards and Recognition • 2012 – Top 10 Critical Care Innovations - Finalist (Medical Device & Diagnostic Industry Magazine) • 2011 – Most Innovative Product (Healthcare Design Magazine) • 2010 – Top 25 Biomed/Biotech Companies in Greater Los Angeles Region • 2009 – Innovation and Best Practices (Frost & Sullivan) • 2008 – “World Changing Ideas” (Palazzo Press) • 2007 – California Tech 100 (State of California) • 2005 – “Homeland Security Award” (Christopher Columbus Foundation) • 2005 – “Top Design Teams in the Nation” (Medical Device and Diagnostic Industry) • 2004 – “Technology Benefiting Humanity” (United Nation’s sponsored Tech Awards) • 2004 – “50 Most Influential Companies” (Fast Company Magazine) • 2003 – “Laufman-Greatbatch Award” (Association for the Advancement of Medical Instrumentation) • 2001 – “Medical Design Excellence Award” (Medical Device and Diagnostic Industry) • 2000 – “Contribution to Healthcare Information” (Stockholm Challenge Awards) • 2000 – “Presidential Design Award” (National Endowment for the Arts) • 2000 – “Innovation in Communication – Healthcare” (Saatchi & Saatchi) • 1999 – “Excellence in Design” (Design News Magazine) 22

  23. The Business –Beachhead Segments Only • Capital Need - $5.50M over 24-30 months to bring first commercial product to market • Pursue in rounds/traunches • Minimum initial round - $1.0M to reduce risks for subsequent rounds • Use of Funds • Product Development: First Commercial Beachhead Product Only • Evaluations: Cellular Connectivity / Iterative Evals / Facilities Impact Simulation • Market Development: Beachhead & Adjacent Market Focus 23

  24. The Business –Penetrating Multiple Segments • Capital Need - $5.50M + $8.00M = $13.50M Total • Use of Funds • Product Development: Product Variants • Evaluations: Expanded Cellular Connectivity /Multiple Product Evals / Facilities Sim • Market Development: Multi-Market Focus 24

  25. Detailed 5 and 10-year projections and financials available upon request 25

  26. Company Summary Proven Management Team – Award-winning successful track record Established Company – Unique healthcare architect Regulatory Clearances – The only ones for integrated systems Existing and Future Product Family – Will transform healthcare No Direct Competitor – Vastly Superior to Status Quo Strong IP Portfolio Exceptional Commercial Market Opportunity Strong Platform for Commercialization Key Relationships – Customers, Suppliers, Collaborators, Thought-Leaders 10X to 50X ROI Low risk of an established company, high return of a start-up: more likely to be successful 26

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