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Energetics of Muscular Activity

Energetics of Muscular Activity. A Chui, Du, Fu, and Truszczynski production. Introduction. 1 muscle fiber = 15 billion filaments 1 filament uses 2500 ATPs/second Can’t store all necessary ATP Resting fiber contains enough ATP to sustain contraction until more can be generated

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Energetics of Muscular Activity

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  1. Energetics of Muscular Activity AChui, Du, Fu, and Truszczynskiproduction

  2. Introduction • 1 muscle fiber = 15 billion filaments • 1 filament uses 2500 ATPs/second • Can’t store all necessary ATP • Resting fiber contains enough ATP to sustain contraction until more can be generated • ATP used at same rate as created

  3. Overview • ATP & CP reserves • ATP Generation (Cellular Respiration) • Muscle Activity • Muscle Fatigue • Muscle Recovery • Hormones & Muscle Metabolism

  4. ATP & CP Reserves • ATP + creatine  ADP + CP • Reverse reaction for use during contraction • Creatine Phosphokinase (CPK) facilitator • Resting fibers contains 6 times as much CP as ATP • 17 second reserves • Table 10-2 Sources of Energy in Fiber

  5. ATP Generation • Glycolysis breaks down glucose to pyruvate in the_________ • Aerobic Metabolism occurs in ________

  6. Muscle Activity Figure 10-15 • Resting Skeletal Muscle • CP + build Glycogen reserves from fatty acids & glucose • Moderate Levels of Activity • All ATP is needed • Peak Levels of Activity (anaerobic) • Lactic Acid fermentation and Glycolysis • Drop pH, exhaustion CP + ATP

  7. Muscle Fatigue • Normal Functioning Requirements • Causes of Muscle Fatigue • ATP & CP • Lactic Acid (anaerobic conditions) • Types of Fatigue • ATP & CP • Lactic acid • Glycogen, aa, lipid reserves • Disorders

  8. Muscle Recovery Period • Lactic Acid Removal and Recycling (Liver & Muscles- Cori cycle) • Oxygen Debt (resp., circ., liver, muscles, secretory) • Heat Loss

  9. Hormones & Muscle Metabolism • Growth Hormone-pituitary • Testosterone • Stimulate synthesis contractile proteins & enlarge muscles • Thyroid Hormones • Elevate rate of energy consumption of muscles • Adrenal Hormones- Epinephrine/Adrenaline • Stimulate muscle metabolism, increase duration of stimulation & force contraction

  10. Questions asdfajhwejkTJjhgawehjkgkmcnvakjrgiorjbalkTJhg8931ATJpeirjh9e4pqrnhbATRJAJATdlfjnkajoawihaATGAJRHEAR;p9ourjhqpGERUAAT0’pi3wtugj4;0kjrhisrtpoATRkojrjoRMTRJNIOJHWOM9UHPER456IW5ESTNAE5JUW45KI56SSRTJ46JRS24fae5Rtwegafbhaeradfbadfawergqr

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