1 / 1

In Vivo Effects of PF502 on MCAS Xenograft Tumor Growth and Signaling Pathways

Study on the impact of PF502 as a single agent on tumor growth and PI3K/mTOR signaling in MCAS xenograft model. Treatment with 10mg/kg PF502. Results analyzed using t-test. Immunoblot of tumors at 19 days shows total ERK levels.

archana-krishnan
Download Presentation

In Vivo Effects of PF502 on MCAS Xenograft Tumor Growth and Signaling Pathways

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. A * B Vehicle PF502 P-AKT total AKT P-PRAS40 P-rpS6 total rpS6 P-ERK Supplementary Figure S2: In vivo effects of PF502 as a single agent on MCAS xenografttumour growth and PI3K/mTORsignalling. MCAS tumour bearing mice were treated daily with vehicle, 10 mg/kg PF502. A, Tumour volume graphed as mean + SEM, n=9-10. Unpaired t test. *, p< 0.0001. B, Immunoblot of tumours harvested at 19 days. total ERK

More Related