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3. 3. 5. 5. Generating Deletions. 5. 3. 5. 3. RS5. RS5r. exon1. Exons 2-6. exon1. 5. 3. 5. 3. RS3. RS3r. exon1. Exons 2-6. Exons 2-6. w +. w -. w -. 3. 5. RS5r. exon1. 5. 3. RS3r. Exons 2-6. w -. DUPLICATION. DELETION. or. exon1. Exons 2-6. w +. w -.

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  1. 3 3 5 5 Generating Deletions 5 3 5 3 RS5 RS5r exon1 Exons 2-6 exon1 5 3 5 3 RS3 RS3r exon1 Exons 2-6 Exons 2-6 w+ w- w- 3 5 RS5r exon1 5 3 RS3r Exons 2-6 w- DUPLICATION DELETION or exon1 Exons 2-6 w+ w-

  2. Coverage maps: Chromosome 3L • Currently, over 10,750 potential deletions can theoretically be made between 100kB and 1MB in length. • Also, over 12,259 deletions between 1bp and 1MB could be constructed.

  3. Validation - Genetic Uncovers noc nht Complements el esg

  4. Df(4)ED6366 M+ CB-5204-3 5-HA-1572 CB-0038-3 Df(4)ED6364 M- Deletions with single gene resolution

  5. CB-5352-3 5-HA-1624 Designer Deletions Df(2R)ED3921 Df(2R)ED3889 UM-8177-3 Andrew Travers, MRC-LMB Cambridge

  6. w1118 RS5r RS3r Gene-trap

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