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Vector yielding PD-1 lo central memory cells. Vector yielding PD-1 hi peripheral memory / effector cells. Epitope-specific T cells. Naïve phenotype. Activated, central memory / reduced effector phenotype. Activated, peripheral memory / enhanced effector phenotype.
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Vector yielding PD-1lo central memory cells Vector yielding PD-1hi peripheral memory / effector cells Epitope-specific T cells Naïve phenotype Activated, central memory / reduced effector phenotype Activated, peripheral memory / enhanced effector phenotype Excessively activated, anergic / exhausted phenotype