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Mutations

Mutations. Mutations. Change in a DNA sequence that affects genetic information. Oohhh…Snap. Mutations. A change in the nucleotide-base sequence. Involve an entire chromosome or a single nucleotide. Germ cell: Occurs in the organism’s gametes. Passed onto offspring. Somatic-cell:

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Mutations

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  1. Mutations

  2. Mutations • Change in a DNA sequence that affects genetic information. Oohhh…Snap.

  3. Mutations • A change in the nucleotide-base sequence. • Involve an entire chromosome or a single nucleotide. Germ cell: Occurs in the organism’s gametes. Passed onto offspring. Somatic-cell: Take place in organism’s own body cell Lethal: Cause death.

  4. Chromosome Mutations • Deletion • Loss of a piece of chromosome

  5. Chromosome Mutation • Inversion • Segment breaks off, flips, and reattaches

  6. Chromosome Mutation • Translocation • Piece breaks off and reattaches to different chromosome

  7. Chromosome Mutations • Nondisjunction • Chromosome fails to separate from its homologous partner during meiosis

  8. Gene Mutations • Point mutations • Change that occurs within a single gene or other DNA segment

  9. Gene Mutations • Substitution • One nucleotide replaces another

  10. Gene Mutations • Frameshift mutation • Loss of nucleotides cause incorrect grouping of codons

  11. Gene Mutations • Insertion mutation • One or more nucleotides are added to a gene, which can also result in a frameshift mutation

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