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The Pharmacology and Physiology of Drug Use

The Pharmacology and Physiology of Drug Use. The relationship of interactions between drugs and living organisms. Pharmacology. Central Nervous System (CNS) Autonomic Nervous System (ANS) Peripheral Nervous System (PNS). The Nervous System. The neuron contains two types of nerve fibers

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The Pharmacology and Physiology of Drug Use

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  1. The Pharmacology and Physiology of Drug Use

  2. The relationship of interactions between drugs and living organisms Pharmacology

  3. Central Nervous System (CNS) Autonomic Nervous System (ANS) Peripheral Nervous System (PNS) The Nervous System

  4. The neuron contains two types of nerve fibers Dendrites – allow nerve impulses to be transmitted to the nerve’s cell body Axoms – send nerve impulses away from the nerve’s cell body Synapse – the space between an axon and a dendrite The Neuron

  5. Action potential – a process by which the nerve impulse is sent down the axon Neurotransmitters – Substances manufactured in the neuron and released into the synapse The Neuron (cont.)

  6. Neurons in the Brain

  7. Synaptic Transmission

  8. Acetylcholine Serotonin Gamma-Aminobutyric Acid (GABA) Catecholamines Reuptake Dopamine Epinephrine/Adrenaline – integral to the Fight-Flight-Fright Mechanism Peptides Neurotransmitters

  9. Fight-Flight-Fright Mechanisms

  10. Reticular activating system (RAS) Hypothalamus Cerebral cortex Limbic system Medial forebrain bundle (MFB) Basal ganglia Periventricular system Brain stem The Central Nervous System (CNS)

  11. Cross Section of the Human Brain

  12. Actions of Various Parts of the Brain

  13. Somatic Nervous System Autonomic Nervous System Sympathetic nervous system Parasympathetic nervous system The Peripheral Nervous System (PNS)

  14. Comparison of Sympathetic and Parasympathetic Systems

  15. Endocrine System Cardiovascular System Respiratory System Gastrointestinal System Drugs and Major Body Systems

  16. Age Gender Dosage Threshold dose Effective dose (ED) Lethal dose (LD) Dose-Response Curve Factors Influencing the Effects of Drugs

  17. Dose-Response Curve

  18. Purity and Potency Drug Interactions Tolerance Pharmacological tolerance Behavioral tolerance Cross-tolerance Reverse tolerance Factors Influencing the Effects of Drugs (cont.)

  19. Set and Setting Factors Influencing the Effects of Drugs (cont.)

  20. Oral ingestion Injection Intravenous injection Intramuscular injection Subcutaneous injection Topical Inhalation Methods of Administration

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