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The Role of Biomarkers in the Management of Sepsis

The Role of Biomarkers in the Management of Sepsis. The Case of Rory Staunton. SIRS. The Spectrum of Sepsis. Code Sepsis at the John Peter Smith Hospital. Incidence and Burden of Sepsis in the United States. Incidence and Burden of Severe Sepsis.

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The Role of Biomarkers in the Management of Sepsis

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  1. The Role of Biomarkers in the Management of Sepsis

  2. The Case of Rory Staunton

  3. SIRS

  4. The Spectrum of Sepsis

  5. Code Sepsis at the John Peter Smith Hospital

  6. Incidence and Burden of Sepsis in the United States

  7. Incidence and Burden of Severe Sepsis

  8. The First Baby Boomers Reached Age 65 in 2011: Portends Increase in Incidence of Sepsis in Future

  9. Future Trend in Incidence of Sepsis Underestimated

  10. Strategies for Improving Sepsis Survival Rates: Early Identification is Critical

  11. Additional Strategies for Improving Sepsis Survival Rates

  12. The Opportunity for Saving Lives With Optimal Sepsis Care Is Greater Than for Therapies for Other Common Conditions

  13. How Reliable is the Diagnosis of Sepsis?

  14. Review of the Literature on Sepsis Biomarkers

  15. Conclusions

  16. The Ideal Sepsis Biomarker

  17. Biomarkers Are Screening Tests or Monitors

  18. Calcitonin Precursors Are Reliable Markers of Sepsis in a Medical ICU

  19. Predictive Accuracy of Biomarkers for Diagnosis of Sepsis in a Medical ICU

  20. Receiver Operating Curve Analysis of Biomarkers for Diagnosis of Sepsis (sensitivity/1-specificity)a

  21. The Positive Likelihood Ratio of PCTa

  22. Value of the Negative Likelihood Ratio

  23. Case: A 17-year-old Boy

  24. Case: A 17-year-old Boy, cont

  25. Case: A 17-year-old Boy, cont

  26. Use of Sepsis Biomarkers in Surgical Patients

  27. Use of Sepsis Biomarkers in Antibiotic Stewardship

  28. Negative-finding Trials of Sepsis Biomarkers

  29. Summary

  30. Abbreviations

  31. Abbreviations (cont)

  32. Abbreviations (cont)

  33. References

  34. References (cont)

  35. References (cont)

  36. References (cont)

  37. References (cont)

  38. References (cont)

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