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Potential conflicts of interest Minimum font size 24pt Please consult your Journal Publishing License Agreement and accordingly choose the correct creative commons attribution license below. Please delete the other option.

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(Title of the manuscript )

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  1. Potential conflictsofinterest Minimum font size 24pt Please consult your Journal Publishing License Agreement and accordingly choose the correct creative commons attribution license below. Please delete the other option. This is an open access article under the CC BY-NC-SA license(http://creativecommons.org/licenses/by-nc-sa/3.0/) This is an open access article under the CC BY-NC-ND license(http://creativecommons.org/licenses/by-nc-nd/3.0/) (Title of themanuscript)

  2. Background Xx Xx Xx Xx Xxminimumfontsize 24pt

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  4. Take Home Message & Impact on Clinical Practice Xx Xx Xx Xx Xxminimumfontsize 24 pt

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