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Physiology of Sleep

Physiology of Sleep. Ahmad Bamagoos MBBS/ M.Sc. Objectives. Function of sleep Regulation of sleep Physiological changes during sleep. Sleep. A reversible behavioral quiescence that is typically accompanied by recumbent posture and irresponsiveness to external stimuli. Function of Sleep.

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Physiology of Sleep

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  1. Physiology of Sleep Ahmad BamagoosMBBS/M.Sc

  2. Objectives • Function of sleep • Regulation of sleep • Physiological changes during sleep

  3. Sleep • A reversible behavioral quiescence that is typically accompanied by recumbent posture and irresponsiveness to external stimuli

  4. Function of Sleep • Survival • Energy conservation • Restoration • Memory consolidation

  5. Arousal System Thalamus Basal forebrain Reticular Formation ARAS

  6. Arousal System - Inhibition Thalamus Basal forebrain VLPO Reticular Formation ARAS

  7. Sleep - Wake Regulation • Circadian drive • Homeostatic drive • Adaptive drive

  8. Sleep - Wake Regulation • Circadian drive - When to sleep - Controlled by circadian rhythm - Circadian clock

  9. Circadian SystemAnatomy & Physiology VLPO Hypothalamus Optic Chiasm SCN Pituitary Gland

  10. Sleep - Wake Regulation • Homeostatic drive - How much sleep - Homeostasis is .. - Sleep-Wake Homeostasis is .. - Hypnotoxins

  11. Sleep - Wake Regulation Homeostatic Drive Circadian Drive 9 am 9 pm Asleep

  12. Sleep - Wake Regulation • Adaptive drive - Psychological factors - Environmental factors - Physical factors

  13. States of Sleep • REM state • nREM state

  14. Physiological ChangesDuring Sleep

  15. Physiological ChangesDuring Sleep

  16. Physiological ChangesDuring Sleep

  17. Physiological ChangesDuring Sleep

  18. Thank You

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