Peptic Ulcer

1. Peptic Ulcer By: Allicia Kwakye Miss Tran TPJ-3MO

2. What is Peptic Ulcer • Ulcer occurs in the gastrointestinal tract • It is acidic and very painful • It caused by a spiral shaped bacterium that lives within the acidic area of the stomach • Ulcers can developed or worsened by drugs such as Aspirin. • Peptic Ulcer emerges frequently in the duodenum rather than the stomach. • Duodenum is the first part of the small intestine

3. Diagram

4. The Cause • Chronic inflammation due to the Helicobacter pylori. It colonizes the antral mucosa. • The bacterium can cause a chronically active gastritis. ( type B), resulting in a defect by the gastrinproduce by that part of the stomach. • NSAIDssuch asibuprofenpenetrates the lining of the stomach and releases substances that damages cells. • NSAIDsalso blocks the natural chemicals (Prostaglandins) that helps and repair those cells. • Chronic stress is strongly associated in the risk of developing Peptic Ulcer • A combination of chronic stress and irregular meal time is significant to this risk of developing Peptic Ulcer. • Also spicy food and alcohol is a risk for developing Peptic Ulcer.

5. Diagram

6. Symptoms • Gnawing or burning pain in the abdomen. This occurs between the breast bone and navel, it is often by pass as a “heartburn”. • Bleeding from the Peptic Ulcer. - Is present during vomiting or in the stool (black stool). • You may experience these symptoms soon after meals: • Pain • Nausea • Pain that radiates to the back • Unusual weakness • Unintended weight loss

7. Treatment • A combination of antibiotics and acid reducing medication such as: • Proton Pump Inhibitors. • Esomeprazole, • Pantoprazole • Rabeprazole • Antibiotics: • Clarithromycin • Amoxicillin • Metronidazole They all should be take twice per day.