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Mendel’s Mighty Missing Meiotic Mechanism

Mendel’s Mighty Missing Meiotic Mechanism. University of North Carolina, Chapel Hill Jean DeSaix Kelly Hogan University of California, Santa Barbra Rolf Christoffersen Stu Feinstein Kansas State University Eva Horne Robbie Bear. With special thanks to Kathrin Stanger-Hall and

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Mendel’s Mighty Missing Meiotic Mechanism

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  1. Mendel’s Mighty Missing Meiotic Mechanism University of North Carolina, Chapel Hill Jean DeSaix Kelly Hogan University of California, Santa Barbra Rolf Christoffersen Stu Feinstein Kansas State University Eva Horne Robbie Bear With special thanks to Kathrin Stanger-Hall and Jess Blum

  2. Teachable Unit: Heredity • Topic: Connecting Meiosis with MendelianInheritance • Context: Large Introductory Biology Course. • Assumed Basic Knowledge: • Chromosome segregation into gametes during meiosis • Mendelian inheritance

  3. Learning Goal : How meiosis relates to the inheritance of alleles of two traits. Learning Outcome for Teachable Tidbit: Predict how the arrangement of chromosomes in meiosis I will determine the allele combinations in a Punnett Square.

  4. Tidbits A = active a = passive B = big b = little AaBb aabb Active & Big passive & little

  5. Tidbit Gonad Single cell a A B b

  6. a Each person = chromosome Color indicates parental origin - pink = maternal origin - blue = paternal origin Letter = allele b A B

  7. Check your vocabulary… What is the relationship between the chromosome carrying the “A” allele and the chromosome carrying the “a”allele? Homologs - same genes, can be different alleles Is a Tidbit gonad cell a diploid or a haploid cell and how do you know? Two sets of all chromsomes. Example: AABB Diploid vs. Haploid One set of all chromosomes. Example: AB

  8. You are all the directors of this show! What needs to happen before we start our production of meiosis?

  9. Check your vocabulary… Homologs - same genes, can be different alleles What is the relationship between the chromatid carrying the “a” allele and the other chromatid attached to it carrying the “a”allele? Sister chromatids - same genes, identical alleles

  10. At metaphase I, how should the alleles be arranged on the metaphase plate? A) B) A A aa A A B B aa b b B B b b C) D) A A aa A A b b aa b b B B B B

  11. At metaphase II, how should the alleles be arranged on the metaphase plate? A) B) A A aa B B A A aa b b B B b b C) D) aa A A aa A A B B b b b b B B

  12. When the actors did this, why did we only get half of the expected types of gametes?

  13. Gonad A A A A aa aa B B B B b b b b A A A A aa aa b b b b B B B B

  14. B) A A aa Homework: Draw the two cells that would result from meiosis I for options B and D. Then draw the outcome of meiosis II for both options B B b b How can we get all of the possible gamete types? D) A A aa b b B B

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