1 / 22

Recife 2014

Cancer Research Center of Toulouse UMR1037 Inserm - Université Toulouse III Paul Sabatier - CNRS. 1-what is it ? 2-who are we ? 3-our mission, our results 4-our project. Recife 2014. Oncopole of Toulouse: a priority of Midi Pyrénées.

colby
Download Presentation

Recife 2014

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Cancer Research Center of ToulouseUMR1037 Inserm - Université Toulouse III Paul Sabatier - CNRS 1-what isit ? 2-who are we ? 3-our mission, ourresults 4-our project Recife2014

  2. Oncopoleof Toulouse: a priority of Midi Pyrénées

  3. Institut Universitaire du Cancer - Oncopole of Toulouse

  4. an innovating architecture to inspiratemultidisciplinaryresearch 8700 m2 of total floor space 5200 m2 research teams (incl. 3549 m2 for 21 modules of 184 m2 ) 800 m2 administration 2700 m2 facilities (incl. 2100 m2animal facility).

  5. Purpan Hospital • Team 07 P. Brousset • Team 08 S. Manenti/C. Récher • Team 09 J.J. Fournié • Protéomics (2/2) • Biological ressources collection • Administration a highly attractive scientifico-medicalenvironment • Claudius Regaud Institute • Team 03 G. Favre • Team 11 E. Moyal/C. Toulas • Team 12 M. Poirot/S. Silvente-Poirot • LBCMCP • Team 01 A. Besson • Rangueil Hospital • Team 04 T. Levade • Team 05 H. Prats • Team 06 S. Pyronnet/C. Bousquet • Team 10 L. Buscail/P. Cordelier • Protéomics (1/2) • Gene vectors • IPBS/CNRS • Team 02 J.S. Hoffmann/C. Cazaux

  6. Who are we ?

  7. 18 research teams, 250 persons, 80 PhDstudents & graduates 10 coretechnologicalplatforms 13,000 cages animal facility

  8. (transgenesis, cryoconservation, genotyping , small animal imaging, …) Mouse Facility CREFRE (UMS006) Experimental Histopathology (CREFRE, CUC, IFR150) Mab production & protein ingeneering (CRCT) Omics (genomics, transcriptomics, proteomics, MS) (CRCT,CUC, IFR150) Gene vectors (CRCT) Cell Imaging (CRCT, IFR150) Bioinformatics (CUC, CRCT) Flow cytometry & cell sorting (CRCT) Analytical Pharmacology (CUC) Biological Resources Collection (CRCT, CUC) Our Coretechnologicalplatforms

  9. 2012: More than 200 people dedicated to cancer research Staff: positions Staff: functions

  10. Leading institutions, leadingresearch Positions Functions 49% 26% 14% 6% 5%

  11. Our Missions , Our results

  12. Our missions • I.Promote an outstandingfundamentalresearch on cancer • II. Acceleratediscovery of new drugs, technologies and treatments • III. Promotescientific, medical & clinicaleducation of students & staff • IV. Accelerateaccess to new clinical trials at IUC • V. Promoteeconomicaldevelopment • (pharma, biotech & othercompanies)

  13. Our results: 5-year indicators of CRCT 22 million € contracts ~1000 publications ~260 graduates 40 patents 3 start-up companies

  14. Departements & thèmes de recherche • Dept 1- Molecularbiology of cancer cells • CDKi as tumor suppressors & oncogenes • geneticinstability of tumor cells • rhoGTPasesregulating cancer cellsignaling • Dept 2- Tumor Biology • metabolism • angiogenesis & lymphangiogenesis • translational control of tumor response to stress • Dept 3- Hematology & Immunology • oncogenesis of T celllymphoma & leukemia • signaling of Acute Myeloid Leukemia • immunotherapy of B lymphomas + new projects • Dept 4- ExperimentalTherapeutics • biomarkers & biotherapies, • therapeutic innovation • tumor radioresistance

  15. Our project Grandes Questions en Oncologie

  16. Mécanismes Oncogéniques

  17. Microenvironnement, Métabolisme, Evolution Tumorale Tumoral structure Cancer CellMetabolism Clonal & MicroenvironmentalCoevolutions

  18. Evolution Clinique & Biomarqueurs Prédictifs

  19. Innovations Therapeutiques BiologicalDrugs Oligonucleotides New ChemicalEntities (Tki, …) Synth peptides Recombproteins Gene therapy Natural products mAbs

  20. Innovations Technologiques

  21. Understandbetter to defeat cancer

  22. … and let’s score the goal together !

More Related