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S ystolic H eart failure treatment with the I f inhibitor ivabradine T rial

S ystolic H eart failure treatment with the I f inhibitor ivabradine T rial. Selective heart rate reduction with ivabradine unloads the left ventricle in heart failure patients. Reil JC, et al. J Am Coll Cardiol . 2013 Nov 19;62(21):1977-1985. www.shift-study.com.

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S ystolic H eart failure treatment with the I f inhibitor ivabradine T rial

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  1. Systolic Heart failure treatment withthe Ifinhibitor ivabradineTrial Selective heart rate reduction with ivabradine unloads the left ventricle in heart failure patients Reil JC, et al. J Am CollCardiol. 2013 Nov 19;62(21):1977-1985 www.shift-study.com

  2. Effect of HR reductionwithivabradine on stroke volume and cardiac output in patients withsystolic HF Cardiac output, ml/min Stroke volume, ml P =0.31 P <0.01 P <0.0001 Baseline Month 8 n=275 Procoralanmaintainscardiac output. Procoralanincreases stroke volume. Reil JC, et al. J Am CollCardiol. 2013 Nov 19;62(21):1977-1985 www.shift-study.com

  3. Ivabradinehas no impact on blood pressure even in the long term NS NS Baseline Blood pressure (mmHg) Month 8 n=275 Reil JC, et al. J Am CollCardiol. 2013 Nov 19;62(21):1977-1985 www.shift-study.com

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