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Schistosomiasis

Schistosomiasis. Schistosoma haematobium Schistosoma mansoni Schistosoma japonicum. A Brief History. First described by German pathologist Theodore Maximilian Bilharz Bilharz performed autopsies on Egyptian patients who had died from the disease:

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Schistosomiasis

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  1. Schistosomiasis Schistosoma haematobium Schistosoma mansoni Schistosomajaponicum

  2. A Brief History... • First described by German pathologist • Theodore Maximilian Bilharz • Bilharz performed autopsies on Egyptian patients who had died from the disease: found male & female parasite eggs in the liver portal system, bladder. • Later seen in Japan, called Katayama fever • Symptoms: rash on legs, fever, diarrhoea, bloody stools  emaciation, edema  death.

  3. Schistosoma • General character: • Morphology • Reproduction system • Importance

  4. Morphology • Size: - Female 12 to 26 mm - Male 6 to 22 mm The three main species infecting humans are Schistosoma haematobium, S. japonicum , andS. mansoni.  Two other species, more localized geographically, areS. mekongiandS. intercalatum

  5. Adult an larve of Sch. Schistosomulum

  6. Geographic Distribution • Schistosoma mansoniis found in parts of South America and the Caribbean, Africa, and the Middle East; • S. haematobiumin Africa and the Middle East; and • S. japonicumin the Far East. • Schistosoma mekongiandS. intercalatumare found focally in Southeast Asia and central West Africa, respectively.

  7. Life Cycle

  8. Schistosoma spp.:miracidium

  9. Schistosoma spp. cercariae are the infective forms. After encountering the skin, the cercariae penetrate and lose the tail transforming into schistosomulae

  10. S. haematobium Biomphalaria

  11. S. mansoni Oncomelania

  12. Miracidium & Cercaria

  13. Liver worm

  14. Schistosoma egg • JK Sch.mansoni egg Sch. japonicum egg Sch. Haematobium egg

  15. Epidemiology of Schistomiasis

  16. Cercarial Dermatitis

  17. Hepatomegaly & splenomegaly

  18. Granuloma( Sch. japonicum egg)

  19. Granuloma( Sch. hematobium egg)

  20. Granuloma

  21. Laboratory Diagnosis • Microscopic identification of eggs in stool or urine is the most practical method for diagnosis. • Stool examination should be performed when infection withS. mansoniorS. japonicumis suspected, • and urine examination should be performed ifS. haematobiumis suspected. Tissue biopsy (rectal biopsy for all species and biopsy of the bladder forS. haematobium) may demonstrate eggs when stool or urine examinations are negative.

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