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Managing Hereditary Angioedema

Managing Hereditary Angioedema. Setting the Stage Burden of Disease in HAE . Burden of Disease in HAE (cont). C1 Esterase Inhibitor for Treatment of Laryngeal Attacks in HAE. Other Therapies Approved For On-Demand Treatment of HAE Attacks. Ecallantide Efficacy. Icatibant FAST-3 Trials.

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Managing Hereditary Angioedema

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  1. Managing Hereditary Angioedema

  2. Setting the StageBurden of Disease in HAE

  3. Burden of Disease in HAE (cont)

  4. C1 Esterase Inhibitor for Treatment of Laryngeal Attacks in HAE

  5. Other Therapies Approved For On-Demand Treatment of HAE Attacks

  6. EcallantideEfficacy

  7. Icatibant FAST-3 Trials

  8. Icatibant Reinjection Rates

  9. C1 Inhibitor Use in Children

  10. C1 Inhibitor Use in Children (cont)

  11. C1 Inhibitor Use in Children for Short-term Prophylaxis

  12. MacGinnitie et al Study of Ecallantide Treatment for Pediatric HAE

  13. Treatment Outcomes With Ecallantide vs Placebo

  14. C1 Inhibitor Dose-escalation Study

  15. C1 Inhibitor Dose-escalation Study (cont)

  16. The Successes in 14 Patients

  17. Treatment Failures

  18. Impact of HAE Prophylaxis on QoL

  19. Effects of C1 Inhibitor Prophylaxis vs On-demand Therapy on QoL

  20. SF-36 Norm-based Domain and Component Summary Scores

  21. Recommendations for Managing HAE

  22. Recommendations for Managing HAE (cont)

  23. Abbreviations

  24. References

  25. References (cont)

  26. References (cont)

  27. References (cont)

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