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Hepatitis Studies. Shyam Kottilil M.D., Ph.D. Laboratory of Immunoregulation National Institute of Allergy and Infectious Diseases National Institutes of Health Department of Health and Human Services Bethesda, MD. Hepatitis C and HIV coexist in the US. IVDU. 100. 5. HCV. 90%. 80. 4.
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Hepatitis Studies Shyam Kottilil M.D., Ph.D. Laboratory of Immunoregulation National Institute of Allergy and Infectious Diseases National Institutes of Health Department of Health and Human Services Bethesda, MD
Hepatitis C and HIV coexist in the US IVDU 100 5 HCV 90% 80 4 60 3 Number affected (millions) Percentage All HIV+ 40 2 33% HIV 20 1 0 0 Population Population Sulkowski MS, Mast EE, Seeff, LB et al. Hepatitis C Virus Infection as an Opportunistic Disease in Persons infected with Human Immunodeficiency Virus. Clin Infect Dis. 2000;30:577-84.
Washington, D.C. Our Nation’s Capital 3%=18000 HIV+ 1.8%=12000 HCV+
Establishment of Hepatitis Clinics Average Incidence Rate per 100,000 Population 0 - 25.0 25.1 – 50.0 50.1 – 75.0 75.1 – 100.0 100.1 – 125.0 Numbers found below each ward refer to the rate of newly reported HIV cases per 100,000 population. Rates were calculated using 2000 Census data. For 16% of cases, ward information was not available and therefore not displayed on this map.
Hepatitis Treatment Protocols-DC-PFAP TLR7 Phase 1 HCV-DAA Natural History Anti-fibrosis GS-7977+RBV HCV DAA Tx Anti-fibrosis Jan June June Sept Sept Dec Mar Mar Anti-fibrosis IFN and RBV FREE Tx Peg+RBV+PI (Boc) TLR7 PHASE 1 HCV-DAA
Washington, D.C. Our Nation’s Capital Most Effective HIV Program Most Effective Hepatitis Program