The Brain

1. The Brain “The Real Health Group” 2 VictoricaRosby Monica Hernandez Bria MarriLyn Monroe Emmanuel Villanueva University of California, Merced

2. Opening discussion question • Scenario of the future where brain-to-body transplants are possible: Bria attempted to commit suicide by laying on the train tracks but the train only ran over her body, leaving her head intact. Paramedics rush to save her and transplant her brain into a new body. • Second scenario of the future where brain to body transplants are possible: Emmanuel attempted to commit suicide by laying on the train tracks but the train only ran over his head (brain), leaving his body intact. Paramedics rush to save him, and transplant a brain into his intact body.

3. Topic Map

4. Dualism • Descartes says dualism-mind and body are separate and do not interact

5. Antonio R. Damasio • Dr. Antonio Damasio graduated from of the University of Lisbon Medical School • He is a member of the Institute of Medicine, of the National Academy of Sciences;  Fellow of the American Academy of Arts and Sciences; a member of the Neurosciences Research Program; a Fellow of the American Academy of Neurology; a member of the American Neurological Association, and of the Association of American Physicians. • He received many scientific prizes • Dr. Antonio Damasio, the Van Allen Professor and Head of Neurology at the University of Iowa, and Adjunct Professor at the Salk Institute, • He had a major influence on our understanding of the neural basis of decision-making, emotion, language and memory, decision-making and consciousness. • His book Descartes' Error: Emotion, Reason and the Human Brain (1994) is taught in many universities worldwide. • Damásio's books deal with the relationship between emotions and feelings, and what their brain substrates. • His 1994 book, Descartes' Error: Emotion, Reason and the Human Brain, won the Science et Vie prize, was a finalist for the Los Angeles Times Book Award, and is translated in over 30 languages.

6. Pop Quiz! • What is dualism?

7. Summary of From Descartes’ Error • From Descartes’ Error: Emotion, Reason, and the Human Brain by Antonio R. Demasio • Case study of Phineas Gage • Man who had an accident with a metal rod that traversed the prefrontal cortex • Prior to injury behavior: Gage was a normal, attentive, well-behaved, man • Post to injury conduct: Gage could not plan, stay focused, engaged in foul language, hesitant and poor decision-making, • In gage’s case the impaired character was dissociated from the otherwise intact cognition and behavior. (p. 65)

8. Quiz • True or False: Did Phineas Gage go to Chile and San Francisco?

9. Oliver Sacks • Oliver Sacks was born in 1933 in London, England into a family of physicians and scientists (his mother was a surgeon and his father a general practitioner). • He earned his medical degree at Oxford University • Since 1965, he has lived in New York, where he practicies neurologist. • From 2007 to 2012, he served as a Professor of Neurology and Psychiatry at Columbia University Medical Center, and was also designated the university’s first Columbia University Artist. • Dr. Sacks is currently a professor of neurology at the New York University,School of Medicine • In 1966 Dr. Sacks began working as a consulting neurologist for Beth Abraham Hospital in the Bronx, a chronic care hospital where he encountered an extraordinary group of patients, many of whom had spent decades in strange, frozen states, like human statues, unable to initiate movement. • The movie the Awakenings was based off of Oliver Sacks

10. Summary from Oliver Sacks • From the Man who mistook his wife for a hat and other clinical tales: By Oliver Sacks • Case Study of Christina • Women diagnosed with gallstones and scheduled for surgery.   • Patient admitted to a hospital 3 days before surgery. • Placed on an antibiotic for microbial prophylaxis • Had a disturbing dream about her body function • “the dream came true” and began having symptoms of “disembodiment”. • She had lost all proprioception, which was caused by an acute polyneuritis (inflammation of several nerves at the same time) • Operation was deferred • Christina’s condition only worsened

11. Quiz! • What movie was based off of Oliver Sacks?

12. Continued summary • Doctors helped Christina regain control and function of her body by teaching her how to substitute her proprioception with vision. Her movement began to become automatism with fluency. • Gained help from visual and auditory feedback • The sense of the body is given by three things: (Normally they all work together. If one sense fails, another will compensate and substitute for everyday function.) • vision • balanced organs • Proprioception • Proprioception: our sixth sense: awareness of the position of one’s body. A connection between state-of-body and state-of-mind. Feeling own body as one’s. • Disembodiment: the lacking proprioception.

13. Question • question: What did Christina dream before her scheduled surgery? • question: Why was Christina going to have surgery?

14. Quiz! • True or False: Phineas Gage was involved in a circus.

15. Work Cited • De Vignemont, F., & Fourneret, P. (2004). The sense of agency: A philosophical and empirical review of the “Who” system. Consciousness and Cognition, 13(1), 1-19. • Gallagher, S. (2000). Philosophical conceptions of the self: implications for cognitive science. Trends in cognitive sciences, 4(1), 14-21. • Straub, R. O. (2007). Health psychology: A biopsychosocial approach. Macmillan.  

16. Links • http://www.jneurosci.org/ • http://www.psychosomaticmedicine.org/ • http://www.sfn.org/annual-meeting/neuroscience-2013

17. Time for another Game! • 1)What portion of the brain did Gage Damage? • A)hippocampus B)frontal lobe C)temporal lobe

18. 2)Who wrote The Man Who Mistook His Wife for a Hat and Other Clinical Tales • A)Descartes B)Antonio R. Damasio C) Oliver Sacks D) Oliver Saxophone

19. 3)Post to Gage injury Gage could not • A)Gage could not plan, stay focused, engaged in foul language, and had poor decision-making B) Gage was Unable to walk, talk, and loss his ability to hear in his left ear. C) All of the above

20. 4) From The Man Who Mistook his Wife for a Hat and other Clinical Tails by Oliver Sacks a 27 year old woman • A)   Woke up with retrograde amnesia • B)    Felt like her body was not hers (felt dead) • C)   She originally had a minor flu that lead to a deadly disorder

21. 5)The title of our readings from chapter 4  The Brain were • a) The Man Who Mistook His Wife for a Hat and Other Clinical Tales and From Descartes’ Error: Emotion, Reason, and the Human Brain • B) From Descartes’ Error: Emotion, Reason, and the Human Brain and Phineas Gage • C) Phineas Gage The Man Who Mistook His Wife for a Hat and Other Clinical Tales

22. Pop Quiz! • What was Descartes’ error?