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The Antitumor Immune Response

The Antitumor Immune Response. Structures of Class I and Class II Major Histocompatability Complex (MHC) Molecules. With permission from Abbas et al. Cellular and Molecular Immunology . 1994. Pathway of Antigen Presentation by Antigen-Presenting Cells.

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The Antitumor Immune Response

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  1. The Antitumor Immune Response

  2. Structures of Class I and Class II Major Histocompatability Complex (MHC) Molecules With permission from Abbas et al. Cellular and Molecular Immunology. 1994

  3. Pathway of Antigen Presentation by Antigen-Presenting Cells

  4. Interactions of the Antigenic Peptide With the Major Histocompatability Complex (MHC) Molecule and the T-Cell Receptor (TCR) With permission from Garcia et al. Science. 1996;274:209.

  5. Role of Costimulation in T-Cell Activation

  6. A B Effector Mechanisms of Tumor Cell Killing by Cytotoxic T Cells (CTLs)

  7. Direct and Indirect Mechanisms Through Which Antitumor Antibody Can Mediate Tumor Cell Killing Directly

  8. Survival Curves of ECOG Trial 1684 With permission from Kirkwood et al. J Clin Oncol. 1996;14:7.

  9. Sources of Antigens for Vaccines Stimulating Cell-Mediated Antitumor Immune Responses

  10. Tumor-Associated Antigen-Based Cancer Vaccines and Roles of Antigen-Presenting Cells (APCs) in Antigen Uptake and Presentation

  11. Scanning Elecron Micrographs of Dendritic Cells, Indicating Some of the Surface Changes Occurring With Maturation Courtesy of Walter Storkus and Robbie Mailliard, University of Pittsburgh School of Medicine.

  12. Antibody Structure and Production of Bispecific and Humanized Monoclonal Antibodies

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