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Purpose of Clinical Chemistry Tests . Measure levels of substances found normally in human blood that have biological functions. Examples: Glucose, CalciumDetect or measure non-functional metabolites or waste products. Examples: Creatinine, Blood Urea Nitrogen (BUN)Detect or measure substances
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1. Lecture 2An overview of Clinical Laboratory Testing Basic Clinical Chemistry
2. Purpose of Clinical Chemistry Tests Measure levels of substances found normally in human blood that have biological functions. Examples: Glucose, Calcium
Detect or measure non-functional metabolites or waste products. Examples: Creatinine, Blood Urea Nitrogen (BUN)
Detect or measure substances that indicate cell damage or disease. Examples: Liver enzymes, such as ALT, Cardiac enzymes, such as CK-MB
Detect or measure drugs or toxic substances. Examples: Dilantin, Drugs of abuse screen
3. Types of Specimens for Chemical Analysis Whole blood, serum or plasma. The most common specimen is serum, collected in a tube with no anticoagulant so that the blood will clot.
Urine often 24 hour collections
Others Cerebrospinal Spinal Fluid (CSF) and other fluids
4. Collection and Handling of Blood Specimens for Chemical Analysis Blood collection tubes for obtaining serum - Serum Separator Tubes (SST) do not have an anticoagulant but do contain a gel substance which will form an interface between the clot and the serum when the blood specimen is centrifuged. These tubes are sometimes referred to as Tiger Tops.