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INFOBIOMED Pilot application WP 6.3

WP 6.3 Genomics and chronic inflammation. INFOBIOMED Pilot application WP 6.3. Genomics and chronic inflammation. Rome, September 14-15, 2006. Marja L. Laine DDS, PhD Academic Centre for Dentistry Amsterdam. 9 th Consortium Meeting, Rome , 14-15 September 2006.

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INFOBIOMED Pilot application WP 6.3

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  1. WP 6.3 Genomics and chronic inflammation INFOBIOMED Pilot application WP 6.3 Genomics and chronic inflammation Rome, September 14-15, 2006 Marja L. Laine DDS, PhD Academic Centre for Dentistry Amsterdam 9th Consortium Meeting, Rome, 14-15 September 2006

  2. Periodontitis is an inflammatory, destructive disease of the supporting tissues of the teeth WP 6.3 Genomics and chronic inflammation use the disease PERIODONTITIS as a model for complex chronic inflammatory diseases 9th Consortium Meeting, Rome, 14-15 September 2006

  3. Genomic data Phenomic data Microbiology data Intermediate phenotype Age Gender BMI CRP, ……… WP 6.3 Genomics and chronic inflammation Environmental /life habits Assessment / Annotation External DBs Programs Periodontitis Data Warehouse (PDW) 9th Consortium Meeting, Rome, 14-15 September 2006

  4. WP 6.3 Genomics and chronic inflammation Periodontitis Data Warehouse - summary • about 800 patients/controls • genetic, microbiology, severity, intermediate phenotype • together with Custodix finalizing the privacy protection • external named user access (VPN-key) • external accessibility (dedicated server) • finalizing stage: data mining, visualization with Forth 9th Consortium Meeting, Rome, 14-15 September 2006

  5. WP 6.3 Genomics and chronic inflammation • ICT for Bio-Medical Sciences, June 2006, Brussels • European Summer school in Biomedical Informatics, July 2006, Hungary • MIE 2006, August 2006, Maastricht, The Netherlands: • Poster and Agost Proceedings, Loos et. al. • Third Training challenge, October 2006,Edingburgh, UK 9th Consortium Meeting, Rome, 14-15 September 2006

  6. WP 6.3 Genomics and chronic inflammation Collaboration with AstraZeneca • INFOBIOMED Mobility funding - Kristina Hettne, Gothenburg How could there be a relation between atherosclerosis and periodontitis? 9th Consortium Meeting, Rome, 14-15 September 2006

  7. WP 6.3 Genomics and chronic inflammation 2007 2004 2005 2006 ACTA, KI, UAVR and ISCIII • Insight in the complex pathophysiology • Clear disease classification schemes • Risk profiling and possibilities for screening ACTA, Custodix, ISCIII, UPM, Astra Zeneca and FORTH September 2006 9th Consortium Meeting, Rome, 14-15 September 2006

  8. WP 6.3 Genomics and chronic inflammation Keep on smiling!!! 9th Consortium Meeting, Rome, 14-15 September 2006

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