Recife, Brazil 67th Brazilian Congress of Cardiology 16 September 2012

1. Update on the Jorge Paulo Lemann Harvard Medical School Cardiovascular Fellowship at Brigham and Women’s Hospital Recife, Brazil67th Brazilian Congress of Cardiology 16 September 2012

3. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship Aims • This fellowship will support full time training in cardiovascular research for physicians or medical scientists who have a commitment from their home institution and convincing possibilities for developing a research career upon return to Brazil.

4. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship Stipend Levels: • The amount of the award will be commensurate with the postdoctoral training scale of the U.S. National Institutes of Health. For current salary levels seehttp://grants.nih.gov/grants/guide/notice-files/NOT-OD-12-033.html • The candidate will need to be responsible for travel and living expenses.

5. National Research Service Award (NRSA) Stipends for Fiscal Year 2012 USD 3272-4515 per month; health insurance and other benefits are provided http://grants.nih.gov/grants/guide/notice-files/NOT-OD-12-033.html

6. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship • Eligibility requirements: • An important part of the selection process is the clear and express official commitment of a Brazilian Institution with a research infrastructure to provide a position for the candidate after his or her return to Brazil and provide support for cardiovascular research, including, if possible, protection of a portion of his or her professional effort exclusively for research.

7. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship • Eligibility requirements: • The candidate him or herself must demonstrate a commitment to research, presented in a brief written statement of career goals.

8. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship Eligibility criteria: 1) Applicants must meet these requirements to be eligible for this Fellowship:a. Physicians (MD) having undertaken a residency in internal medicine or cardiology.b. Scientists with a PhD in cardiovascular or allied research. 2) Preference will be given to candidates who have demonstrated involvement and commitment to cardiovascular research. Early career researchers will be given priority. 3) Candidates who have already performed a research fellowship in the United States are not eligible to compete for the award.

9. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship Documents needed for application 1) Curriculum vitæof the candidate. 2) Letter from a Brazilian institution with a research infrastructure indicating commitment to the candidate's career, describing the steps that will be taken to support their research, such as providing financial resources and facilities for research, and protecting time for the candidate to perform research upon return to Brazil. 3) A personal statement by the candidate describing their interest in cardiovascular research and how the Lemann Fellowship would help in his or her career. 4) Three letters of reference.

10. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship Selection Process: The selection will be conducted by a Committee of faculty members of Brigham and Women's Hospital, Cardiovascular Division chaired by Prof. Peter Libby. The Fellowship will be managed and administered by the Cardiovascular Division at Brigham and Women's Hospital in coordination with Harvard Medical School. The Fellows will be provided with a benefit package from Brigham and Women’s Hospital.

11. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship • Downloadable application form available at http://www.brighamandwomens.org/cvcenter/Lemann_Fellowship.aspx • The documents required for the application should be scanned and submitted as PDFs with the application form.

12. http://www.brighamandwomens.org/cvcenter/Lemann_Fellowship.aspxhttp://www.brighamandwomens.org/cvcenter/Lemann_Fellowship.aspx

13. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship • Only applications written in English will be accepted, and must be sent electronically by e-mail: dlynn@rics.bwh.harvard.edu and received by 17:00 on 12/31/2012. • For further information, contact David Lynn at dlynn@rics.bwh.harvard.eduor by telephone: 617-525-4351.

14. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship • Fourth Cycle Call: • Deadline: December 31, 2012 (by 17:00) • Number of awards available: 1 or 2 • Beginning of the Fellowship: Between March and July 2013 • Duration of Grant: 2 years

15. Current and PastJorge Paulo Lemann Cardiovascular Research Postdoctoral Fellows • Julio FlavioMarchini • AyumiMiakawa • MárcioSommersBittencourt • Marina Moreira

20. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship • Important points: • Open competition - all candidates have equal consideration • We seek diversity, both geographical and institutional • Fellows are fully integrated with the >100 research fellows in the Brigham Cardiovascular Division

21. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship • Important points: • The award will not support clinical practice training, BUTwe encourage applicants with interest in eitherclinical or basic research training

22. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship • Important points: • The research done in Boston can be used for a DoutoradoSanduiche thesis, pending pre-arrangement with the Brazilian institution.

23. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship • Important points: • Applicants need not identify a research mentor a priori: Dr. Libby will help match the fellows with the appropriate laboratories or projects

24. Jorge Paulo Lemann Cardiovascular Research Postdoctoral Fellowship • The BWH web site describes the range of faculty mentors and research available to LemannFellows:http://www.brighamandwomens.org/research/depts/medicine/cardiovascular/default.aspx

25. http://www.brighamandwomens.org/research/depts/medicine/cardiovascular/default.aspxhttp://www.brighamandwomens.org/research/depts/medicine/cardiovascular/default.aspx

26. Cardioavscular Division Brigham & Women’s Hospital • 87 Faculty • ~25 core “clinical” fellows • 147 fellows overall

27. Brigham & Women’s Hospital Cardiovascular Clinical Research • TIMI (Braunwald, et al.) • Preventive medicine (Ridker et al.) WHS, HPS,JUPITER • Pfeffer/Solomon (SAVE, PEACE, VALIANT, TREAT etc.)

28. Brigham & Women’s Hospital Cardiovascular Clinical Research • HCRI: Laura Mauri Dual antiplatelet trial (DAPT), MassDAC Registries on DES etc.

29. Brigham & Women’s Hospital Cardiovascular Basic Research • Vascular: • Gimbrone, Libby, Loscalzo, Michel , Lee, Plutzky

30. Brigham & Women’s Hospital Cardiovascular Basic Research • Myocardial/Genetics: • Seidmans, Lee, Macrae

31. Brigham & Women’s Hospital Cardiovascular Basic Research • Regenerative: • P Anversa, RT Lee

32. A teaching affiliate of Harvard

35. Shapiro Cardiovascular Center

36. Update on the Jorge Paulo Lemann Harvard Medical School Cardiovascular Fellowship at Brigham and Women’s Hospital Recife, Brazil67th Brazilian Congress of Cardiology 16 September 2012