Treating Premature Ejaculation: Dapoxetine Hydrochloride Powder

1. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 Content 1. What is Dapoxetine hydrodhloride powder? ........................................ 1 2. How does Dapoxetine hydrochloride work? ......................................... 5 3. Dapoxetine hydrochloride other name ................................................. 6 4. What is Dapoxetine hydrochloride use for? ......................................... 6 5. What is Premature Ejaculation(PE)? ..................................................... 7 6. How to use Dapoxetine hydrochloride powder 丨 Dapoxetine dosage 8 7. Dapoxetine hydrochloride effects? ..................................................... 10 8. Dapoxetine VS Tadalafil ...................................................................... 12 9. Is it safe to take dapoxetine hydrochloride? ....................................... 15 10. Dapoxetine side effects ..................................................................... 18 11. Buy Dapoxetine hydrochloride powder ............................................ 19 1. What is Dapoxetine hydrodhloride powder? Dapoxetine hydrochloride powder also write as dapoxetine HCL powder, it is hydrochloride type of dapoxetine. Dapoxetine hydrochloride powder is

2. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 white crystaline powder, CAS No. is 129938-20-1. Dapoxetine HCL powder is a new antidepressant, has been found to be safe and effective for the treatment of premature ejaculation, according to two major clinical trials. Dapoxetin is a short-acting selective serotonin reuptake inhibitor (SSRI). It is not uncommon for SSRIs to be used off-label for premature ejaculation. Premature ejaculation (PE) is the most common male sexual dysfunction with a prevalence of between 20% and 40%. Recently, the International Society for Sexual Medicine has proposed the following evidence-based definition:“PE is a male sexual dysfunction characterized by ejaculation that always or nearly always occurs prior to or within about 1 minute of vaginal penetration; inability to delay ejaculation on all or nearly all vaginal penetrations; and negative personal consequences, such as distress, bother, frustration, and/or the avoidance of sexual intimacy". In addition, PE affects numerous aspects of a man's life, including sexual confidence, interpersonal relationships, and the sexual satisfaction of both partners. The role of PE on the individual and the sexual relationship is very significant. Thus, it is important to treat patients with Premature ejaculation(PE) in order to improve quality of life. At present,

3. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 treatment of PE includes mainly psychotherapy, drug therapy, and surgical treatment6. Drug therapy is not only likely to be the most receptive approach for patients, but it is also the most commonly used method. Selective serotonin reuptake inhibitors (SSRIs) have become the most widely used medicine in the world. Dapoxetine hydrochloride, belonging to the class of SSRIs, was the first drug originally approved for the on-demand treatment of men with PE by seven European countries in 2008. Dapoxetine powder description Name Dapoxetine hydrochloride, Dapoxetine hydrochloride CAS 129938-20-1 Molecular Formula C9H7ClN2O5 Molecular Weight 258.62 Melt Point 175-179°C Storage Temp -20°C Freezer Color White crystalline powder Dapoxetine HCL is a short-acting novel selective serotonin reuptake inhibitor, used for the treatment of premature ejaculation.Dapoxetine not only reduces the peak amplitude of Kv4.3 currents but also accelerates the decay rate of current inactivation in a concentration-dependent manner. Dapoxetine decreases the integral of the Kv4.3 currents over the duration of a depolarizing pulse with an IC50 of 5.3 μM. Dapoxetine also causes a substantial acceleration in Decription

4. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 closed-state inactivation. Dapoxetine produces a significant use-dependent block, which is accompanied by a delayed recovery from inactivation of Kv4.3 currents. Dapoxetine decreases the peak amplitude of Kv1.5 currents and accelerates the decay rate of current inactivation in a concentration-dependent manner with an IC50 of 11.6 μM. Dapoxetine decreases the tail current amplitude and slows the deactivation process of Kv1.5, which results in a tail crossover phenomenon. Dapoxetine produces a use-dependent block of Kv1.5 at frequencies of 1 and 2 Hz and slowed the time course for recovery of inactivation.Dapoxetine also appears to be a useful adjunct to morphine, lowering the threshold for analgesia, although Dapoxetine itself has negligible analgesic activity. Dapoxetine is the D-enantiomer of LY 243917 and is 3.5 times more potent as a serotonin reuptake inhibitor than the L-enantiomer Package method foil bag or customization Delivery method Fedex, DHL, EMS, post...etc Guarantee period around 3years under the correct storage condition Delivery time within 12 hours after payment Payment mtehod WesternUnion,MoneyGram,Bitocin,Bank transfer Picture

5. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 2. How does Dapoxetine hydrochloride work? Dapoxetine mechanism of action? The mechanism through which dapoxetine affects premature ejaculation is still unclear. However, it is presumed that dapoxetine works by inhibiting serotonin transporter and subsequently increasing serotonin's action at pre and postsynaptic receptors Human ejaculation is regulated by various areas in the central nervous system (CNS).The ejaculatory pathway originates from spinal reflex at the thoracolumbar and lumbosacral level of spinal cord activated by stimuli from male genital. These signals are relayed to the brain stem, which then is influenced by a number of nuclei in the brain such as medial preoptic and paraventricular nulcei.Clement's study performed on anaesthetized male rats showed that acute administration of dapoxetine inhibits ejaculatory expulsion reflex at supraspinal level by modulating activity of lateral paragigantocellular nucleus (LPGi) neurons. These effects cause an increase in pudendal motoneuron reflex discharge (PMRD) latency. However, it is unclear whether dapoxetine acts directly on LPGi or on the descending pathway in which LPGi located.

6. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 3. Dapoxetine hydrochloride other name Dapoxetine hydrochloride/Dapoxetine HCL marketed as Priligy and Westoxetin, among and other brands. 4. What is Dapoxetine hydrochloride use for? Dapoxetine hydrochloride powder/Dapoxetine HCL powder use for treat premature ejaculation in men aged 18 to 64 years. Priligy tablets contain the active ingredient raw dapoxetine hydrochloride powder, which is a type of medicine known as a selective serotonin reuptake inhibitor. It is used to treat premature ejaculation in men. Raw dapoxetine hydrochloride powder works by increasing the activity of serotonin in the nervous system. Serotonin is a neurotransmitter that is involved in passing messages between nerve cells. It has various functions in the body and is involved in sending the nerve messages that result in ejaculation. Increasing the activity of serotonin in the nervous system helps to increase the time it takes to ejaculate and improve control over the ejaculation.The medicine is taken a couple of hours before you intend to have sex to help you last longer before you climax.

7. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 The research team examined the results of two trials, totalling 2,614 men. All the men had from moderate to severe premature ejaculation - on average, the men were ejaculating within one minute of penetration. Half of them were randomly selected to receive Dapoxetine while the other half received a placebo. Both groups had to take their medication from 1 to 3 hours before sexual intercourse. After three months, the men taking a 30-milligram dose of dapoxetine took an average 2.78 minutes to ejaculate after penetration, those on a 60-milligram dose took 3.32 minutes. The placebo group averaged 1.75 minutes (after three months). 5. What is Premature Ejaculation(PE)? In lay terms it means 'coming too quickly' (for a man). The man ejaculates sooner than he or his partner would like. It is common for this to happen now and again. It is seen as a problem for many men and some of their partners if this happens regularly. It is the most common male sexual dysfuntion - estimated to affect about 20% of males in the USA aged 18-59.

8. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 The problem is thought to be psychological. However, it can also be biological. Premature ejaculation has two classifications: Primary Premature Ejaculation The man has experienced premature ejaculation throughout his sexually active life. Secondary Premature Ejaculation The condition has developed after the man used to have satisfying sex without ejaculatory problems. 6. How to use Dapoxetine hydrochloride powder丨 丨Dapoxet ine dosage Dapoxetine hydrochloride powder for sale online also, the makers buy dapoxetine hydrochloride powder for sale online, then mix it and make into dapoxetine tablets or other products. How to use dapoxetine?Dapoxetine dosage?

9. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 -One dapoxetine tablet should be taken one to three hours before sexual activity. -The dapoxetine tablet can be taken either with or without food. It should be swallowed whole to avoid getting a bitter taste from the tablet. The dapoxetine tablet should be taken with a full glass of water. -Dapoxetine tablet should not be taken more than once every 24 hours. It should only be taken when sexual activity is anticipated and is not intended as a regular treatment that is taken each day. -The recommended dapoxetine dosage is 30mg(dapoxetine 30mg). If this is not effective enough your doctor may increase your dapoxetine dosage to 60mg(dapoxetine 60mg), but this should only be done if you have not experienced any side effects with the lower dose. -Your doctor will discuss your treatment with you after four weeks or six dapoxetine dosage of treatment. If treatment with dapoxetine is continued your doctor will need to see you every six months. Dapoxetine dosage: dapoxetine 30mg and dapoxetine 60mg

10. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 7. Dapoxetine hydrochloride effects? How long does dapoxetine last? What are dapoxetine hydrochloride effects? The following summary data are taken from the article Dapoxetine: a new option in the medical management of premature ejaculation McMahon, Chris G, Ther Adv Urol. 2012 October; 4(5): 233-251, where the author presents information and results of clinical trials of dapoxetine. We encourage physicians and patients to read the entire document丨dapoxetine research. The most comprehensive results from this work comes from the Phase III studies that included 6,081 subjects ranging in age from 18-82. In a double-blind study, each of roughly one-third of patients received one of the following dapoxetine doage: dapoxetine 30mg, dapoxetine 60 mg, or a placebo. Effects of Dapoxetine on IELT Inter-Vaginal Latency Time For men with an average baseline IELT of 0.9 minutes, the average IELT

11. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 improved to 3.1 minutes for a 30mg dose and 3.6 minutes for a 60 mg dose. Patients taking the placebo improved to 1.9 minutes. Ejaculation-Related Sexual Satisfaction % Good/Very Good Ejaculatory Control The first of the subjective scores is the subject's feeling of having ejaculatory control. The per cent of subjects that believed that they had"good" or "very good" control is shown in this chart.

12. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 8. Dapoxetine VS Tadalafil There are many kinds of sex enhancing powder, such as tadalafil powder, sildenafil powder, avanafil powder,vardenafil powder...etc. What are the difference between them? Dapoxetine, tadalafil, sildenafil, avanafil, Name Dapoxetine HCL powder Tdalafil PE is a condition where a man ejaculates too quickly during sex, causing distress to himself or his partner. PE is usually defined as sex lasting less than two minutes before the man orgasms. If it suits a couple to have a short ejaculation period, then this is not Tadalafil powder is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, tadalafil works by increasing blood flow to the penis to help a man get and Treatment

13. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 PE and does not need treatment. There are various causes for PE, the most common being a simple inability to control ejaculation. In some men, medical problems such as prostate problems or hypothyroidism can result in PE. Relationship worries or anxiety can also cause PE to develop. In young men, PE often improves as sexual experience increases. keep an erection. Tadalafil is also used to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH). It helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate frequently or urgently (including during the middle of the night). Tadalafil is thought to work by relaxing the smooth muscle in the prostate and bladder. Tadalafil offers no protection against sexually transmitted diseases dapoxetine 30mg, dapoxetine 60mg Dosage 20-30mg For most individuals, the recommended starting dose of tadalafil is 10 mg per day taken before sexual activity (tadalafil for use as needed). Depending on the adequacy of the response or side effects, the dose may be increased to 20 mg or decreased to 5 mg a day. The effect of tadalafil may last up to 36 hours. Individuals who are taking medications that increase the blood levels of tadalafil should not exceed a total dose of 10 mg in 72 hours. For once daily use without regard to sexual activity One tablet should be taken one hour before sex. It can be taken with or without food. You should not take alcohol when you use Priligy. Never take more than one tablet within a 24 hour period. Priligy is only licensed in men between the ages of 18 and 64 who have had PE for at least six months. Usage

14. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 the recommended dose is 2.5 to 5 mg daily. Tadalafil should not be taken more than once daily. Dapoxetine affects actions of chemicals in the brain that encourage ejaculation. It works best during the one to three hours after it is taken but can sometimes retain its effects for up to 12 hours. Tadalafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body. Mechanism of action Tadalafil powder tends to take effect more quickly than other ED drugs, with onset of effectiveness within 30 minutes typically. The recommendation is to take tadalafil powder 30 minutes prior to sexual activity, while with sildenafil citrate (viagra)and vardenafil powder(Levitra), users are instructed to take the drug 60 minutes before sexual activity. Generally, the effects of tadalafil powder last 24 to 36 hours after taking it. The fact that the effects are so long-lasting has been a major selling point for tadalafil powder, which branded itself “the weekend pill.” Many men like that they can take tadalafil Friday night, and still experience its effects Sunday morning. The extended duration of tadalafil's effects allows for more spontaneity and less guesswork about when to take it. The majority of men will experience an increase in the time between getting an erection and ejaculation. Dapoxetine works in around 8 out of 10 men. These men should notice a doubling or tripling of the time their erection lasts before ejaculation. Dapoxetine is not a cure and will only work when you take it. Effect Side effects Dapoxetine is only advised for common tadalafil side effects may

15. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 men who ejaculate in less than two minutes of penetration. It should not be taken by men who have heart disease, those who have a tendency to faint or in those who take certain medicines (your doctor will be aware of which medicines this applies to). This is because more serious side effects can occur. include:headache;flushing (warmth, redness, or tingly feeling);nausea, upset stomach;stuffy nose; or muscle pain, back pain, pain in your arms or legs. The most common side effects are nausea, dizziness, headache, fainting and diarrhoea. A full list of side effects will come with your medication or you can click here to read the manufacturers advice. If you feel dizzy or faint after taking Dapoxetine then you should not drive, operate heavy machinery or undertake hazardous activities. Tadalafil is currently the most-prescribed of the three top ED medications available in the US. Though most men take Cialis on an as-needed basis, a daily dosing option is available, and offers some men relief from ED they might not experience otherwise. Who can take it 9. Is it safe to take dapoxetine hydrochloride? The main evidence for the effectiveness of dapoxetine can be found in a large dapoxetine research review conducted by Dr Chris G McMahon in 2012. He reviewed 5 different major studies which involved over 6000 men in total. His main findings were:

16. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 For men who last an average of 0.9 minutes, a 30 mg dose increased that to 3.1 minutes A 60 mg dose increased it to 3.6 minutes Patients on a placebo increased to 1.9 minutes A significant number of men reported that their premature ejaculation was better with dapoxetine Dr McMahon also reviewed how many of the 6000 men experienced side effects with the drug. The percentage of men who experienced side effects with the 30 mg dose were: Nausea – 11% Dizziness – 5.8% Headache – 5.6% Diarrhea – 3.5% Nasopharyngitis – 3.2% Somnolence – 3.1% Insomnia – 2.1% Fatigue – 2% And with the 60 mg dose:

17. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 Nausea – 22.2% Dizziness – 10.9% Headache – 8.8% Diarrhea – 6.9% Nasopharyngitis – 2.9% Somnolence – 4.7% Insomnia – 3.9% Fatigue – 4.1% This was far more than with the placebo, for example just 2.2% had nausea. And the highest was headaches, with 4.8% of men having them with the placebo. In addition to these common side effects, there were also reports of a very small number of men experiencing snycope: In concluding, Dr McMahon does state though that dapoxetine is safe to use for the majority of men.

18. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 You should be aware that it does come with warnings that you shouldn’t take it if you have certain health conditions. That’s why it’s so important to discuss taking it with a doctor first. 10. Dapoxetine side effects What are the side effects of dapoxetine hydrochlorde 丨 Dapoxetine side effects?And what can I do when experience dapoxetine side effects? Side effects of Dapoxetine hydrochloride Very common dapoxetine side-effects (these affect more than 1 in 10 men) What can I do when experience Sit with your head between your knees, or lie down until the feeling passes Feeling dizzy or light-headed These are signs that fainting may occur. Sit down until the feeling passes so that you do not fall and hurt yourself Feeling sick, sweaty or confused Ask your doctor or pharmacist to recommend a suitable painkiller Headache

19. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 11. Buy Dapoxetine hydrochloride powder It's a personal choice to buy dapoxetine hydrochloride powder online 丨 buy dapoxetine HCL powder or not. However, it's a choice which comes with risks attached. There are a number of dapoxetine HCL powder supplier 丨 dapoxetine HCL powder manufacturer selling dapoxetine HCL powder; there are also a worryingly large number of dapoxetine HCL powder supplier 丨 dapoxetine HCL powder manufacturer online selling counterfeit products. Are you sure you can tell the difference between a trustworthy dapoxetine HCL powder source and a fake dapoxetine HCL powder source just from their website? If you're determined to buy dapoxetine HCL powder online, then here are some things to consider: -If the website looks bad, is very small or selling nothing other than dapoxetine hydrochloride powder, then look elsewhere. -Do some background checks on the company name of the website.

20. Treating Premature Ejaculation : Dapoxetine hydrochloride powder www.aasraw.com aas15@aasraw.com, Whatsapp:+8618902484839 -Some counterfeit drugs are ineffective, so you may end up wasting your money. Click here to buy high quality dapoxetine HCL powder from AASraw