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This project investigates the impact of obesity on hospital costs using quantile regression. The study analyzes the length of stay and cost variations among obese inpatients in Australian hospitals. Results highlight differences across hospital specialties, episode types, and outlier management for accurate cost estimation.
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Modelling the impact of being obese on hospital costs Katharina Hauck Bruce Hollingsworth A project funded by the NHMRC (grant number 334114) and the ARC (grant number DP0772235)
Background • Cost of obesity (and related co-morbidities) to the health care system are a concern • Studies may underestimate the economic cost of obesity • Obesity directly causes illnesses which are costly to treat • Obesity may also influence the progression or severity of other illnesses, including ones which are not directly caused by obesity
Research Question and Approach • Is it more costly to treat obese patients, once they are in hospital? • Difference in cost irrespective of type of illness and procedure? • Analyse impact on length of stay (LOS) of inpatients • LOS is major determinant of hospital costs • Generate different estimates over the whole distribution of LOS (from one night to very long)
Data • Australian administrative public hospital data ‘Victorian Admitted Episodes Data’ (VAED) for 2005/06 • Analysis on patient level • Patient defined as obese if one of 2nd to 12th diagnosis code falls within the range of ICD codes "E660“ to "E669“ • Our sample: financial year 2005/06 with 461,563 inpatients, of which 6,086 (1%) are obese
Model • LOS = f (obese, age, gender, nonelective, private payer, index of social advantage, cost weight, number of diagnoses and procedures, total separations of hospital, type and location of hospital) • Coefficient on dummy variable ‘obese’ is estimate of impact of obesity (+ more costly, - less costly) • Analysis for selected hospital specialties, and for medical and surgical admissions
Problem: Outliers • Problem: upper and lower outliers with respect to LOS • In VAED: 3.4% of Patients stay very long and 1.3% very short, conditional on observable characteristics • Outlier status established with OLS regression of LOS on explanatory factors • Observations are • Lower outliers if resOLS< Q(25) - 3*Inter Quartile Range • Upper outliers if resOLS > Q(75) + 3*Inter Quartile Range
Estimation: Quantile Regression • Problem: Large proportion of outliers violates assumptions of normality of Ordinary Least Squares Regression • Solution: Quantile regressions on 19 quantiles of LOS • Quantiles of the conditional distribution of LOS are expressed as functions of observed covariates • Quantiles range from 0.05 (very short LOS) to 0.95 (very long LOS), including the median 0.5
Estimation: Quantile Regression • Quantile regression minimizes a sum of absolute residuals • Residuals are weighed asymmetrically (for all quantiles except the median) • According to quantile, differing weights are given to positive and negative residuals • Outliers do not bias estimates at other quantiles • Quantile regressions allow for differing impact of being ‘obese’ at various points of the distribution of LOS
Why have obese different LOS? • Why do obese stay longer in some specialties, but shorter in others? • Possible answers: • Obese stay longer when they are treated as a medical case because they are more complex? • Obese stay shorter when they are treated as a surgical case because they are much more complex, and are transferred to another hospital (risk/cost shifting), or even die? Any ideas?
Future Research • Investigatereasonsfor cost differences • Analyse reasons for different patterns across specialties • Use data on: - Transfers to other hospitals - Readmissions (to the same, and different hospitals) - Complications andadverse events - Mortality rates (in-hospital, and 30 day after stay)
Probit estimations • Difference in probability of being transferred to another hospital when obese, conditional on other explanatory factors • Negative effect (?!) of ‘obese’ for Haematology, Respiratory and Endocrinology, insignificant for all other specialties • Difference in probability of dying when obese, conditional on other explanatory factors • Negative effect (?!) of ‘obese’ for the whole sample, and a range of specialities including Orthopaedics, Cardiology, General Medicine, and General Surgery.