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Heart Electrical Activation

Heart Electrical Activation. By: Elnaz Shokrollahi Supervisors: Dr. S. Krishnan Dr. K. Nanthakumar. Signal Propagation in Heart. Stimulus originates in the SA node and travels across the walls of the atria, causing them to contract.

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Heart Electrical Activation

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  1. Heart Electrical Activation By: ElnazShokrollahi Supervisors: Dr. S. Krishnan Dr. K. Nanthakumar

  2. Signal Propagation in Heart • Stimulus originates in the SA node and travels across the walls of the atria, causing them to contract. • Stimulus arrives at the AV node and travels along the AV bundle • Stimulus descends to the apex of the heart through the bundle branches • After stimulus reaches the Purkinje fibers, the ventricles contract.

  3. Tachycardia (Fast Heartbeat) Bradycardia (Slow Heartbeat) Cardiac Arrhythmia • Cardiac arrhythmia is when the electrical activity of the heart is irregular (faster/slower) than normal. Ventricular Fibrillation

  4. Cardiac ElectroPhysiology (EP)

  5. Conventional EP Mapping • Point-by-point mapping acquisition. • Direct voltage mapping. • Many Disadvantages: • Identification of areas of low voltage is time-consuming catheter manipulation. • Focal lesion creation may not be sufficient to ablate VT conduction through a broad isthmus region. • Identification breakthrough points may be challenging.

  6. Non-contact Mapping • Catheter of its own. • Non-contact mapping uses unipolar Virtual Electrograms (VE)

  7. Illustration of Geometry and Position of Paced Areas

  8. Electrogram • Recording of cardiac potentials • from electrodes directly in contact • with the heart.

  9. Time-Domain Analysis • -Peak Negative Voltage (PNV) in (mV) • -Maximal Negative dV/dt (mV/ms) • -Area Under the Curve (AUC) • -Presence of an initial R-wave • -Duration • -Presence of low-amplitude depolarization

  10. Results of Time-Domain Analysis

  11. Frequency- Domain Analysis • FFT requires large quantities of data to produce significant result. • AR modeling

  12. Results of Classification Results with AR Coefficients

  13. Conclusions • Presented electrographic parameters. • Morphologies of electrograms allowed the discrimination of endo/epicardially paced activation. • Possibility of combination of the criteria will improve the perception over any single criterion. • Allow to detect tachycardia originating epicardially using noncontact mapping.

  14. Brain Storming Thank you for your attention!

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