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Different views of bioinformatics. CS view: what are the algorithms, data structures and other concepts needed to develop tools to solve biological problems Biologist view: how to use tools to solve typical problems of interest in biology
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Different views of bioinformatics • CS view: what are the algorithms, data structures and other concepts needed to develop tools to solve biological problems • Biologist view: how to use tools to solve typical problems of interest in biology • More theoretical view: what new algorithms are suggested by biological applications
Too much for one quarter Genomics: DNA, RNA Protein structure, function and interactions Drug design Algorithms for sequence alignment Tree representations of relationships Gene microarrays Proteomics/Mass spec Protein structure prediction
Our runner-up course book "Protein Bioinformatics : An Algorithmic Approach to Sequence and Structure Analysis"Ingvar Eidhammer; Hardcover; $69.86 • Takes the CS point of view • Limited to issues regarding proteins • Too many errors for my comfort zone
Background reference "Protein Stucture and Function (Primers in Biology)” Gregory A. Petsko and Dagmar Ringe; Paperback; $47.66 Excellent material on basic biology (great pictures!) but not bioinformatics. • Describes how proteins function • Good reference for biochemistry of proteins and their function
Biologist-focused book "Bioinformatics and Functional Genomics" Jonathan Pevsner; Paperback; $72.16 • “First class had 80 grad students and several hundred auditors” at Johns Hopkins • Presents “how to use” bioinfo tools from the perspective of a biomedical researcher • Not so much on how the algorithms work but a good way to see how they are used
Comprehensive reference "Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins, Third Edition"Andreas D. Baxevanis and B. F. Francis Ouellette, eds; Hardcover; $60.00 This is an edited collection of essays by experts on the use of different bioinfo tools in different areas. Intended as a reference (not a textbook)
Just the algorithms "An Introduction to Bioinformatics Algorithms (Computational Molecular Biology)” Neil C. Jones; Hardcover; $42.67 • More of a focus on algorithms, with less coverage of applications • The next step in the CS direction in bioinformatics (e.g., PhD level course)