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Vinita Allee Henry, OD, FAAO. Disinfecting Soft Lenses. Thermal Disinfection (not used) Chemical Disinfection Oxidative Disinfection. Advantages Convenient Simple Compliance. Disadvantages Preservatives Disinfection time Cost Little effect on AIDS/Acanthamoeba. Chemical Disinfection.
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Disinfecting Soft Lenses • Thermal Disinfection (not used) • Chemical Disinfection • Oxidative Disinfection
Advantages Convenient Simple Compliance Disadvantages Preservatives Disinfection time Cost Little effect on AIDS/Acanthamoeba Chemical Disinfection
Preservatives used to Disinfect • Must not be toxic to the ocular tissue • Must demonstrate ability to kill bacteria
Polyquad Aldox Isopropanol H2O2 Dymed (PAPB) Polyhexamethylene Biguanide Polyhexanide Preservatives/Disinfectants
Redness Itching Burning Dryness Lens Intolerance Decreased WT Sensitivity Symptoms
Recalls • ReNu Moisture Loc Alexidine preservative • Complete Moisture Plus
Fusarium keratitis • Started in Asia • 17 states in US, not MO • 30 cases in US, 26 admitted ReNu or B&L generic products • Recalled ReNu MoistureLoc off shelves • Tx: Natacyn (natamycin 5%)
Fusarium keratitis • The classic description of fungal keratitis is a grayish-white corneal infiltrate with a rough, dry texture and feathery borders. Satellite lesions are common and hypopyon and endothelial plaque may also be observed. Intact and slightly elevated epithelium overlying a deep stromal infiltrate may also be seen.
Signs and Symptoms • Red and irritated eyes lasting for an unusually long period of time after lens removal • Pain in and around the eyes especially if it progressively worsens • Increased sensitivity to light • Rapid onset of blurred or fuzzy vision • Excessive tearing or discharge
Top 6 Recommendations for Clean and Safe Contact Lenses • Always wash your hands before handling contact lenses. • Carefully and regularly clean contact lenses, as directed by your optometrist. If recommended, rub the contact lenses with fingers and rinse thoroughly before soaking lenses overnight in sufficient multi-purpose solution to completely cover the lens. • Store lenses in the proper lens storage case and replace the case every three months. Clean the case after each use, and keep it open and dry between cleanings. • Use only products recommended by your optometrist to clean and disinfect your lenses. Saline solution and rewetting drops are not designed to disinfect lenses. • Only fresh solution should be used to clean and store contact lenses. Never re-use old solution. Contact lens solution must be changed according to the manufacturer's recommendations, even if the lenses are not used daily. • Always replace old contacts when you get a new contact lens prescription. When wearing or cleaning contacts: • Never put contact lenses in the mouth or moisten them with saliva, which is full of bacteria and a potential source of infection. • Don't use tap water or homemade saline solutions. Improper use of solutions has been linked to a potentially blinding condition among soft lens wearers. • Never use contacts that have not been prescribed by an eye doctor. Contact lens wear is not an option for everyone; consult with an optometrist to see if contact lenses are an appropriate choice for vision correction.
Patient Care Nuggets • Cleaning: Rubbing vs. Rinsing • Long-term Storage • Overnight Storage • Lubricating the Lenses • Dry Eyes
Advantages: Rapid Effective No preservatives Cleans & bleaches Disadvantages: Costly More complicated Punctate keratitis Oxidative Disinfection
Oxidative Disinfection • H2O2 is changed to H2O and Oxygen by a catalyst • Can use dilution • What about brown bottle peroxide
Patient Care Nuggets • Cleaning with oxidative disinfection • Pink indicator • Storage
Alternative Disinfection • Purilens – UV Radiation • Lensoclean – Ultrasonic
Lens Care • Aquify (Ciba Vision) • Must rub the lenses with MPS • Presoak lenses to improve wettability
Lens Care • Andrasko Staining Grid (staining assessed after 2 hrs. of wear & overnight soaking) • IER Matrix Study (staining evaluated 3 times over 3 mth. DW period)
Comparison of IER Matrix study with Andrasko Staining Grid(Taken from Mack CJ. Contact Lenses 2007, CLS 23(1):32.)
Lens Care • Ciba Vision study compared ClearCare to OF Replenish, OF Express, Complete MoisturePlus, ReNu MultiPlus with O2 Optix, PureVision, AV Advance and Oasys- 187 subjects • Conclusion: ClearCare was superior for comfort at insertion, end-of-day and preventing irritation at the end of the day.
Source of Deposits • Moist lens • Surface quality of the lens • Poor blinking/tears • Poor cleaning • Hands • Environment
Deposits cause: • Decreased preservative action • Decrease oxygen • Alters parameters/increased movement • Decrease wetting • Decreased WT • Red eyes • Discoloration
Protein- White/opaque Lipids- greasy Jelly bumps – white elevated bumps Most Common Deposits
Other Deposits: • Pigment deposits • Microorganism growth • Rust spots
Surfactant Cleaners • Used Daily • Remove lipids • Use upon lens removal • Rub the lens in a back & forth manner • Rubbing is better than rinsing
Soft Lens Daily Cleaners for those Deposit-Prone Patients • Miraflow • Opti-Free Daily Cleaner
99% of Acanthamoeba can be removed by rubbing and rinsing prior to disinfection.
Enzymatic Cleaners • Use for traditional replacement lenses • Use for deposit-prone patients • Remove protein • Once a week, or daily enzymatic cleaners • Combination solutions- Disinfect and remove proteins
Enzymatic Cleaners • Ultrazyme • Unizyme • Supra-Clens (also OF RepleniSH rewetting drops)
Lubricants • Blink-N-Clean (AMO) • Clerz Plus, OF Replenish Drops (Alcon) • Aquify (Ciba) • Blink Contacts(AMO) • Refresh Contacts (Allergan) • Theratears (Adv. Vision Research)
Lens Lubricants Use: • EW • Dry eyes • FB • Do not substitute GP ones or other products
Patient Education • Hygiene • Cosmetics • Facial Products • Other Nuggets
Hand washing Tap water Good magnification for those > 40 Foreign body particles Insertion & Removal Holding those lids Always insert the same lens first Avoid rubbing lens in circular motion General Tips for Handling Soft Lenses
Patient Hygiene • Hand Washing • Wash thoroughly prior to handling the lenses • Hand Soaps • Use antibacterial soaps without lotions • Case Cleanliness • Replace the case every 3 months • Dump solution & allow to air dry