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Tay-sachs-Disease

Tay-sachs-Disease. By: Cory Hawkins & Tj Cartwright. Tay-Sachs- Disease. Where harmful quantities of ganglioside builds up Causes infants to die at an early age People show no sign. Pedigree of disease. What causes tay-sachs-disease?. Mutations in the HEX A causes TSD

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Tay-sachs-Disease

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  1. Tay-sachs-Disease By: Cory Hawkins & Tj Cartwright

  2. Tay-Sachs- Disease • Where harmful quantities of ganglioside builds up • Causes infants to die at an early age • People show no sign .

  3. Pedigree of disease

  4. What causes tay-sachs-disease? • Mutations in the HEX A causes TSD • Build up of GM2 ganglioside • In that leads to destruction of nerve cells

  5. How common is it? • It’s a very rare disease • 25% chance from infant inheriting the disease • Most common in eastern Europe

  6. Every day life • Carrier shows no sign of disease • Live normal life • They carry disease for their entire life

  7. Treatment • No treatment • Working on a cure • Might never actually find a cure

  8. Physical symptoms • Physical symptoms only in children • People show no sign • Live a normal life • Infants lose the ability to crawl and smile etc.

  9. Life expectancy • Life expectancy is usually very old • Infants die before age of 4 • Parents who carry the disease live a normal life and show no sign

  10. Inheritance • Autosomal recessive • Polygenic trait • Complete dominance

  11. Resources cited • ghr.nlm.nih.gov/condition • www.teachersdomain.org/9-12/ sci/life/gen/lp_disorder/index.html • www.ntsad.org/pages/t-sachs.htm • http://www.marchofdimes.com/professionals/681_1227.asp

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