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Research in Biomedicine and Health – I. Day 2 Seminar Types of research articles. Original research article new knowledge for the first time. Other types of articles in journals : Case report Review article Editorial material : Editorials Commentaries Viewpoints Letter to editor
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Researchin Biomedicine and Health – I Day 2 Seminar Types of research articles
Original research article new knowledge for the first time
Othertypesofarticlesinjournals: Casereport Reviewarticle Editorialmaterial: Editorials Commentaries Viewpoints Letter to editor Book or mediareview
Design of analyticalstudies • Observational studies • Cross-sectional / prevalence • Case-control / retrospective • Cohort / prospective • Experimental studies • Controlled clinical trials
Hierarchy of evidence • N of 1 randomized control trial • Systematic reviews of randomized control trials • Single randomized control trial • Systematic review of observational (cross-sectional, cohort, or case-control) studies • Single observational (cross-sectional, cohort, or case-control) study • Physiologic studies (studies of blood pressure, cardiac output, exercise capacity, bone density, etc) • Unsystematic clinical observations (case series, case report)
Experimental research Cohort study Typesofstudydesingaccording to the time-frame Time of study group formation Cross-sectional study Time of data collection Case control study Historical cohort study sadašnjost prošlost budućnost Past Present Future
Hierarchy of evidence • http://www.cebm.net/index.aspx?o=1025 • Centre for Evidence Based Medicine, University of Oxford • Levels of evidence for: • Therapy / Prevention, Aetiology / Harm • Prognosis • Diagnosis • Differential diagnosis / symptom prevalence study • Economic and decision analyses
http://www.ted.com/talks/ben_goldacre_battling_bad_science?language=enhttp://www.ted.com/talks/ben_goldacre_battling_bad_science?language=en