Question 1

3. Question 1 What percentage of IVF cycles in your laboratory have embryo biopsy performed for preimplantation genetic sequencing (PGS)? 1)      0% 2)      0-25% 3)      25-50% 4)      50-75% 5)      75-100%

5. Question 2 At the PGD laboratory you use, are embryos primarily tested with: 1)      Array comparative genomic hybridization (aCGH) 2)      SNP microarray 3)      Quantitative, real-time PCR 4)      Next Generation Sequencing

7. Question 3 What do you believe is the most common cause of implantation failure in a euploid embryo transfer? 1)Subchromosomal abnormalities 2)       Embryo transfer technique 3)       PGS platform errors 4)       Endometrial factors 5) Non-genetic embryonic factors

9. Question 4 Does the PGD laboratory you employ report mosaicism and segmental deletions/duplications? 1)      Yes 2)      No

11. Question 5 Would you ever transfer an embryo with predicted mosaicism? 1)      Yes 2)      No

13. Question 6 Should PGD laboratories report suspected diagnoses of subchromosomal aneuploidies (copy number variants)? 1)      Yes 2)      No

15. Question 7 Should infertile couples (without a recurrent pregnancy loss history) routinely have a karyotype performed before IVF? 1)      Yes 2)      No