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Schizophrenia: biological

Schizophrenia: biological. www.psychlotron.org.uk. Genetics Structural brain abnormality Neurochemistry. Schizophrenia: genetics. www.psychlotron.org.uk. Prevalence of schizophrenia is the same all over the world (about 1%)

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Schizophrenia: biological

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  1. Schizophrenia: biological www.psychlotron.org.uk • Genetics • Structural brain abnormality • Neurochemistry

  2. Schizophrenia: genetics www.psychlotron.org.uk • Prevalence of schizophrenia is the same all over the world (about 1%) • Supports a biological view as prevalence does not vary with environment • However, there are variations within broad geographical areas (e.g. Torrey 2002 – Croatia & Ireland) • Urbanicity data

  3. Schizophrenia: genetics www.psychlotron.org.uk Source: Gottesman (1991)

  4. Schizophrenia: genetics www.psychlotron.org.uk • Risk rises with degree of genetic relatedness • Spouse – 1% (same as G.P.) • Child – 13% • DZ twin – 17% • MZ twin – 48% • Effect of shared environment?

  5. Schizophrenia: genetics www.psychlotron.org.uk • Adoption studies

  6. Schizophrenia: genetics www.psychlotron.org.uk • Substantial evidence for a genetic contribution • Some evidence disputed: • Shared environment issues • Diagnostic criteria in adoption studies • All the evidence also suggests environmental triggers

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