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Bottom Line

This study reveals that even breast pathology experts struggle with reproducibility in diagnosing intraductal proliferative lesions, particularly in the ADH/limited LG-DCIS realm. The significance of ADH vs. DCIS has fewer management implications than UDH vs. ADH. Morphology alone is still heavily relied upon, but IHC can sometimes be helpful. When in doubt, send it out for consultation or share with colleagues.

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Bottom Line

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Presentation Transcript

  1. Bottom Line • Diagnostic reproducibility in the range of intraductal proliferative lesions is poor • Even amongst breast pathology experts • Even when specific criteria are used • Particularly in the ADH/limited LG-DCIS realm • Significance on the core of ADH vs DCIS has fewer management implications than UDH vs ADH. • Still rely heavily on morphology alone. • Deepers, IHC can sometimes help. • So if in doubt, send it out! Or share.

  2. Post-quiz

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  4. 2. 0.1 cm

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  9. Answers Pre-quiz Post-quiz 1. UDH 2. ADH 3. DCIS 4. FEA 5. UDH 1. UDH 2. ADH 3. ADH 4. UDH 5. FEA 6. CCC

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