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Clinical intervention algorithm in the SafeBoosC trial

Clinical intervention algorithm in the SafeBoosC trial. rStO 2 < 55%. rStO 2 > 85%. Blood Pressure. Consider volume expansion, vasopressor/inotropes, decrease MAP. CRT. Clinical assessment. Lactate. On vasopressors?. Urine output. Consider reducing vasopressor. Cardiovascular status.

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Clinical intervention algorithm in the SafeBoosC trial

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  1. Clinical intervention algorithm in the SafeBoosC trial rStO2 < 55% rStO2 > 85% Blood Pressure Consider volume expansion, vasopressor/inotropes, decrease MAP CRT Clinical assessment Lactate On vasopressors? Urine output Consider reducing vasopressor Cardiovascular status Consider volume expansion, inotropes, decrease MAP Low CO/ SVC flow Echocardiography PDA Consider treatment Oxygen transport [Hb] low Consider RBC transfusion Consider increase FiO2 Consider decrease FiO2 SaO2high SaO2 low Respiratory status Respiratory status PCO2 low Consider decrease MV Consider increase MV PCO2high Consider increase glucose intake Blood glucose level Low

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