Supplemental figure 4

Oct 27, 2014

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Supplemental figure 4

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Supplemental figure 4

Supplemental figure 4

A. B. C. D. Supplemental figure 4. Supplemental Figure S4. Kinetics of total IFN γ + (A), IL-2+ (B) and TNFa+ (C) CD4+ and IFN γ + (D) CD8+ T-cell responses in KTRs during the clinical course of BKV re-activation

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Supplemental Figure 1

Supplemental Figure 1. Fig. S1 qRT -PCR analysis of the genes flanking the sbp2’ / sbp2’’ knockouts. All values are given relative to the abundance of transcript observed in P1/7. Data presents the mean from 3 biological replicates. .

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Supplemental Figure 3

Supplemental Figure 3. Purified Collagens. A). B). Purified Collagen1 ( μ g). 0.12. 0.25. 0.5. 1. 2.5. 5. 10. 20. Purified Col1. Purified Col3. Col1. Purified Collagen3 ( μ g). Col1. 0.12. 0.25. 0.5. 1. 2.5. 5. 10. 20. Col3. Col3. Col1. Col3. Arbitrary Units.

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Supplemental Figure 4

Supplemental Figure 4. a. Succinate Succinate+ADP Succinate+Oligo Succinate+FCCP. b. Succinate Succinate+ADP Succinate+Oligo Succinate+FCCP. p <0.05. p <0.05.

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Supplemental Figure 1

Supplemental Figure 1. d-ROM (Carr U). P = 0.0512. recurrence-free period (day). Correlation between d-ROM levels and recurrence-free period in 36 multicentric occurrence cases using linear regression analysis.

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Supplemental Figure 1

Supplemental Figure 1.

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Supplemental Figure 3

Supplemental Figure 3. Time course of mean arterial pressure, albuminuria, and kidney injury after reduction in renal mass and treatment of C57BL/6 mice with deoxycorticosterone acetate + saline drinking water (DOCA) or treatment of CD-1 mice with hydralazine.

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Supplemental Figure 1

Supplemental Figure 1. A. P-VEGFR2. Tubulin. PlGF-1 250 ng/mL - + + + + Time (min) - 5 10 15 30. B. P-VEGFR2. Tubulin. C.

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Supplemental Figure 5

Supplemental Figure 5. A. MTLn3 GFP-CXCL12. MTLn3 GFP-pQCXIP. C. B. ***. CXCR4. IgG. % of max. BMM Chemotaxis to CXCL12. % of max. CXCR4-PE. CXCR4-PE. IgG. CXCR4. B.

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Supplemental Figure 2

MK-1775. MK-1775 + 37.5 nM MK-8776. MK-1775 + 75 nM MK-8776. MK-1775 + 150 nM MK-8776. MK-1775 + 300 nM MK-8776. Supplemental Figure 2. A. B. HRE cells. fractional proliferation. MK-8776 ( μ M). MK-1775 ( μ M).

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Supplemental Figure 5

Trastuzumab-treated. Control-treated. A. MDA-MB-453. 14.2%. 10.7%. DEAB-inhibited. DEAB-inhibited. B. JIMT-1. 5.2%. 5.4%. DEAB-inhibited. DEAB-inhibited. C. Sum159-HER2. 7.1%. 36%. DEAB-inhibited. DEAB-inhibited. Trastuzumab-treated. Control-treated. D. Supplemental Figure 5.

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Supplemental Figure 2

si RNA #1. si RNA #1. si RNA #1. si RNA #1. si RNA #2. si RNA #2. si RNA #2. si RNA #2. si RNA #3. si RNA #3. si RNA #3. si RNA #3. si control. si control. si control. si control. Casp-9. Casp-2. 47kDa. 51kDa. b -actin. b -actin. Relative mRNA expression. RAIDD. PIDD.

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Supplemental Figure 4

Supplemental Figure 4. a. 1000, 2000, 4000, 8000 cells/well into 96 well dish. 10, 20, 40, 80 cells/well into 96 well dish. R.L.U. measurement. R.L.U. measurement. CellTiter-Glo. CellTiter-Glo. 10% FBS DMEM. 10% FBS DMEM. 7 days. 6 hr. co llagen concentration.

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Supplemental Figure 1

Supplemental Figure 1. True leaf from 2 nd to 7 th nodes. (a). M. 1 st (IN) IN. 2 nd. 3 rd. 4 th. 5 th. 6 th. 7 th. PC. ALSV-RNA2. 7. PsEF1- a. 6. 1. 2. 3. 5. True leaf from 2 nd to 7 th nodes. ALSV inoculation. 4. 2 nd. 3 rd. 4 th. 5 th. 6 th. 7 th. 3. Mock. 2.

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Supplemental Figure.

Supplemental Figure. Legend:

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Supplemental Figure 4

A. Panc5.04. A10.7. A38.44. ***. **. ***. ***. ***. **. **. **. B. C. Panc5.04. A38.44. ADM NDRG-1. ***. **. **. Vehicle (10%FBS) Vehicle (1%FBS) SB202190 (10%FBS) SB202190 (1%FBS). Vehicle (10%FBS) Vehicle (1%FBS) SB202190 (10%FBS) SB202190 (1%FBS). Vehicle (10%FBS)

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Supplemental Figure S 4

A. B. D. C. F. E. Supplemental Figure S 4.

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Supplemental Figure 4

Supplemental Figure 4.

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Supplemental Figure 3

Supplemental Figure 3.

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SUPPLEMENTAL FIGURE 4

SUPPLEMENTAL FIGURE 4.

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Figure I supplemental

Figure I supplemental.

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Supplemental Figure 2

Supplemental Figure 2. a. ADP titration (Clark-type electrode). ~10.00. ~10.27. ~7.01. ~5.11. ~5.00. ~4.03. ADP titration (Seahorse XF24). b. ~3.89. ~3.10. ~2.62. ~2.03. ~1.63. c. Mitochondrial integrity test (Clark-type electrode). d.

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